ReviewAnnual review of genetics2019
Multigenerational Regulation of the
Review in Annual review of genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Review
- Reproductive phasiRNAs are the piRNAs of plants.Trends in genetics : TIG · 2026Review
- Germ granule localization of nematode Argonaute WAGO-4 ensures fidelity in small RNA loading.The EMBO journal · 2025Article
- Maternal vitamin B1 is a determinant for the fate of primordial follicle formation in offspring.Nature communications · 2023Article
- miRNA/siRNA-directed pathway to produce noncoding piRNAs from endogenous protein-coding regions ensuresScience advances · 2023Article
- Inheritance of associative memories and acquired cellular changes in C. elegans.Nature communications · 2023Article
- RNA-mediated heterochromatin formation at repetitive elements in mammals.The EMBO journal · 2023Review
- Unique Features of Satellite DNA Transcription in Different Tissues ofInternational journal of molecular sciences · 2023Article
- Structural and functional organization of germ plasm condensates.The Biochemical journal · 2022Review
- Transcriptional Stress Memory and Transgenerational Inheritance of Drought Tolerance in Plants.International journal of molecular sciences · 2022Review
- The conserved helicase ZNFX-1 memorializes silenced RNAs in perinuclear condensates.Nature cell biology · 2022Article
- The Caenorhabditis elegans TDRD5/7-like protein, LOTR-1, interacts with the helicase ZNFX-1 to balance epigenetic signals in the germline.PLoS genetics · 2022Article
- Nematode chromosomes.Genetics · 2022Review
- Small RNA pathways in the nematode Ascaris in the absence of piRNAs.Nature communications · 2022Article
- Long RNA-Mediated Chromatin Regulation in Fission Yeast and Mammals.International journal of molecular sciences · 2022Review
- The role of RNA-binding proteins in orchestrating germline development inFrontiers in cell and developmental biology · 2022Review
- Nuage condensates: accelerators or circuit breakers for sRNA silencing pathways?RNA (New York, N.Y.) · 2022Review
- Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality.Cell reports · 2021Article
- Heritable shifts in redox metabolites during mitochondrial quiescence reprogramme progeny metabolism.Nature metabolism · 2021Article
- Small RNAs and chromatin in the multigenerational epigenetic landscape ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
In animals, small noncoding RNAs that are expressed in the germline and transmitted to progeny control gene expression to promote fertility. Germline-expressed small RNAs, including endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), drive the repression of deleterious transcripts such as transposons, repetitive elements, and pseudogenes. Recent studies have highlighted an important role for small RNAs in transgenerational epigenetic inheritance via regulation of heritable chromatin marks; therefore, small RNAs are thought to convey an epigenetic memory of genomic self and nonself elements. Small RNA pathways are highly conserved in metazoans and have been best described for the model organism
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.