ArticlePloS one2019
Comparative genome analysis indicates high evolutionary potential of pathogenicity genes in Colletotrichum tanaceti.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Microalgae as a Novel Therapy for Chronic Wound Healing.International wound journal · 2026Review
- Plant Pathogenic and EndophyticMicroorganisms · 2025Review
- Isolation and Biological Control ofJournal of fungi (Basel, Switzerland) · 2025Article
- Phylogenomics and adaptive evolution of the Colletotrichum gloeosporioides species complex.Communications biology · 2025Article
- From Natural Hosts to Agricultural Threats: The Evolutionary Journey of Phytopathogenic Fungi.Journal of fungi (Basel, Switzerland) · 2025Review
- Comparative Genomic Analyses ofJournal of fungi (Basel, Switzerland) · 2024Article
- Social wasp-associated Tsukamurella sp. strains showed promising biosynthetic and bioactive potential for discovery of novel compounds.Scientific reports · 2024Article
- Complete genome of the Medicago anthracnose fungus,Microbial genomics · 2024Article
- Unveiling the Arsenal of Apple Bitter Rot Fungi: Comparative Genomics Identifies Candidate Effectors, CAZymes, and Biosynthetic Gene Clusters inJournal of fungi (Basel, Switzerland) · 2024Article
- Evolutionary history of the cytochrome P450s from Colletotrichum species and prediction of their putative functional roles during host-pathogen interactions.BMC genomics · 2024Article
- What lies behind the large genome ofFrontiers in fungal biology · 2024Article
- Comparative Genomic Analysis ofJournal of fungi (Basel, Switzerland) · 2023Article
- Publicly Available and Validated DNA Reference Sequences Are Critical to Fungal Identification and Global Plant Protection Efforts: A Use-Case inPlant disease · 2022Article
- Comparative Genomics of ThreeFrontiers in microbiology · 2022Article
- Proteinaceous Effector Discovery and Characterization in Plant PathogenicFrontiers in microbiology · 2022Review
- Identification and Comparison ofPathogens (Basel, Switzerland) · 2021Article
- Article
- Comparative Genomics Analyses of Lifestyle Transitions at the Origin of an Invasive Fungal Pathogen in the GenusmSphere · 2020Article
- Colletotrichum shisoi sp. nov., an anthracnose pathogen of Perilla frutescens in Japan: molecular phylogenetic, morphological and genomic evidence.Scientific reports · 2019Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Colletotrichum tanaceti is an emerging foliar fungal pathogen of commercially grown pyrethrum (Tanacetum cinerariifolium). Despite being reported consistently from field surveys in Australia, the molecular basis of pathogenicity of C. tanaceti on pyrethrum is unknown. Herein, the genome of C. tanaceti (isolate BRIP57314) was assembled de novo and annotated using transcriptomic evidence. The inferred putative pathogenicity gene suite of C. tanaceti comprised a large array of genes encoding secreted effectors, proteases, CAZymes and secondary metabolites. Comparative analysis of its putative pathogenicity gene profiles with those of closely related species suggested that C. tanaceti likely has additional hosts to pyrethrum. The genome of C. tanaceti had a high repeat content and repetitive elements were located significantly closer to genes inferred to influence pathogenicity than other genes. These repeats are likely to have accelerated mutational and transposition rates in the genome, resulting in a rapid evolution of certain CAZyme families in this species. The C. tanaceti genome showed strong signals of Repeat Induced Point (RIP) mutation which likely caused its bipartite nature consisting of distinct gene-sparse, repeat and A-T rich regions. Pathogenicity genes within these RIP affected regions were likely to have a higher evolutionary rate than the rest of the genome. This "two-speed" genome phenomenon in certain Colletotrichum spp. was hypothesized to have caused the clustering of species based on the pathogenicity genes, to deviate from taxonomic relationships. The large repertoire of pathogenicity factors that potentially evolve rapidly due to the plasticity of the genome, indicated that C. tanaceti has a high evolutionary potential. Therefore, C. tanaceti poses a high-risk to the pyrethrum industry. Knowledge of the evolution and diversity of the putative pathogenicity genes will facilitate future research in disease management of C. tanaceti and other Colletotrichum spp.
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