ArticlePLoS computational biology2019
State-aware detection of sensory stimuli in the cortex of the awake mouse.
Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Spiking neural networks provide accurate and time-efficient models for whisker stimulus classification of the awake mouse.Frontiers in neuroscience · 2026Article
- Layer 6 Corticothalamic Neurons Induce High Gamma Oscillations Through Cortico-cortical and Cortico-thalamo-cortical Pathways.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Impairment in the homeostatic recruitment of layer 5/6 neurons following whisker stimulation in Fmr1 KO mice.Neurobiology of disease · 2025Article
- Dynamic corticothalamic modulation of the somatosensory thalamocortical circuit during wakefulness.Nature communications · 2024Article
- kCSD-python, reliable current source density estimation with quality control.PLoS computational biology · 2024Article
- A machine learning approach for real-time cortical state estimation.Journal of neural engineering · 2024Article
- Latent dynamics of primary sensory cortical population activity structured by fluctuations in the local field potential.Frontiers in computational neuroscience · 2024Article
- Endogenous fluctuations in cortical state selectively enhance different modes of sensory processing in human temporal lobe.Nature communications · 2023Article
- Aligning latent representations of neural activity.Nature biomedical engineering · 2023Article
- Thalamic bursting and the role of timing and synchrony in thalamocortical signaling in the awake mouse.Neuron · 2022Article
- Spatiotemporally resolved multivariate pattern analysis for M/EEG.Human brain mapping · 2022Article
- Ipsilateral Stimulus Encoding in Primary and Secondary Somatosensory Cortex of Awake Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Modulation in cortical excitability disrupts information transfer in perceptual-level stimulus processing.NeuroImage · 2021Article
- Spectral signature and behavioral consequence of spontaneous shifts of pupil-linked arousal in human.eLife · 2021Article
- Rapid Cortical Adaptation and the Role of Thalamic Synchrony during Wakefulness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Thalamic state influences timing precision in the thalamocortical circuit.Journal of neurophysiology · 2021Article
- State-space optimal feedback control of optogenetically driven neural activity.Journal of neural engineering · 2021Article
- Cortical State Fluctuations during Sensory Decision Making.Current biology : CB · 2020Article
- Neuromodulation of Brain State and Behavior.Annual review of neuroscience · 2020Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Cortical responses to sensory inputs vary across repeated presentations of identical stimuli, but how this trial-to-trial variability impacts detection of sensory inputs is not fully understood. Using multi-channel local field potential (LFP) recordings in primary somatosensory cortex (S1) of the awake mouse, we optimized a data-driven cortical state classifier to predict single-trial sensory-evoked responses, based on features of the spontaneous, ongoing LFP recorded across cortical layers. Our findings show that, by utilizing an ongoing prediction of the sensory response generated by this state classifier, an ideal observer improves overall detection accuracy and generates robust detection of sensory inputs across various states of ongoing cortical activity in the awake brain, which could have implications for variability in the performance of detection tasks across brain states.
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