Evidence map›Paper›PMID 31150258›Full record

ArticleOrganic letters2019

Solid-Phase-Supported Approach for the Preparation of Bioresponsive and Multifunctional MRI Probes.

Liam Connah, Rajendra Joshi, Sandip Vibhute, Giuseppe Gambino, João D G Correia, Goran Angelovski

Abstract read
In one paragraph

Article in Organic letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. RGD-Peptide Functionalization Affects theJournal of medicinal chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liam Connah
Rajendra Joshi
Sandip Vibhute
Giuseppe Gambino
João D G CorreiaCentro de Ciências e Tecnologias Nucleares, Departamento de Engenharia e Ciências Nucleares , Instituto Superior Técnico, Universidade de Lisboa , CTN, Bobadela LRS , Portugal.ORCID 0000-0002-7847-4906

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of bifunctional imaging probes can often be challenging with difficult and time-consuming solution phase chemistry protocols and purification techniques. A solid phase synthetic protocol was therefore utilized to produce a functionalized derivative of a potent bismacrocyclic calcium-responsive contrast agent for magnetic resonance imaging. Through a convenient building block approach, the applicability of this methodology in the preparation and simple future development of multifunctional imaging probes was demonstrated.

Indexed as

Magnetic Resonance ImagingContrast MediaMacrocyclic CompoundsContrast MediaMacrocyclic Compounds

Identifiers

PMID31150258
PMCPMC6750874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.