Evidence map›Paper›PMID 31150164›Full record

ReviewCancer cytopathology2019

Cytologic features of aggressive variants of follicular-derived thyroid carcinoma.

Esther Diana Rossi, William C Faquin, Liron Pantanowitz

Abstract readReview
In one paragraph

Review in Cancer cytopathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Thyroid cytology: practical tricks and pitfalls.Virchows Archiv : an international journal of pathology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Cytomorphological study of thyroid carcinoma.Experimental and therapeutic medicine · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Esther Diana RossiDivision of Anatomic Pathology and Histology, Catholic University of Sacred Heart, Rome, Italy.ORCID 0000-0003-3819-4229
William C FaquinDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Liron PantanowitzDepartment of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.ORCID 0000-0001-8182-5503

Funding

Strategies to Overcome Immune Resistance in Head and Neck CancersP01CA240239 · NCI · YALE UNIVERSITY · PI MEMPEL, THORSTEN ROMAN · 2019 to 2023
$8.4M
NCI NIH HHS P01 CA240239
6 · The paper itself

Abstract

Certain carcinomas of the thyroid gland behave aggressively resulting in increased patient morbidity and poor patient prognosis. The diagnosis of these aggressive thyroid cancer subtypes is sometimes challenging and subject to increased interobserver variability. This review deals with the cytological features of such tumors including aggressive variants of papillary thyroid carcinoma, poorly differentiated thyroid carcinoma, and anaplastic thyroid carcinoma. These malignancies fall into 2 groups based on their cytomorphology: those that exhibit distinct microscopic features (eg, nuclear findings typical of classical papillary thyroid carcinoma or marked anaplasia) and those that present with more subtle cytologic features (eg, nuclear pseudostratification, "soap bubble" nuclei, supranuclear or subnuclear cytoplasmic vacuoles, rosette-like structures, hobnail cells). We review the literature regarding these aggressive thyroid cancers and highlight important phenotypic characteristics that can be useful for their diagnosis based on fine needle aspiration.

Indexed as

Adenocarcinoma, FollicularBiopsy, Fine-NeedleDiagnosis, DifferentialHumansPrognosisThyroid Cancer, PapillaryThyroid Carcinoma, AnaplasticThyroid GlandThyroid Neoplasmsaggressive variantsanaplastic carcinomafine needle aspiration cytologypersonalized medicinepoorly differentiated carcinomathyroid cancer

Identifiers

PMID31150164
PMCPMC7478176

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.