ArticleDiabetic medicine : a journal of the British Diabetic Association2019
Diabetic foot ulcer incidence and survival with improved diabetic foot services: an 18-year study.
Article in Diabetic medicine : a journal of the British Diabetic Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Global Epidemiology of Diabetic Foot: A Systematic Review and Meta-Analysis.Diabetes/metabolism research and reviews · 2026Pooled it
- Prevalence and Incidence of Diabetes-Related Peripheral Neuropathy, Peripheral Artery Disease, Foot Ulcers and Lower Extremity Amputations in Ireland; A Systematic Review.Journal of foot and ankle research · 2026Pooled it
- Prevalence of plantar ulcer and its risk factors in leprosy: a systematic review and meta-analysis.Journal of foot and ankle research · 2023Pooled it
- Footwear and insole design features for offloading the diabetic at risk foot-A systematic review and meta-analyses.Endocrinology, diabetes & metabolism · 2021Pooled it
- Effect of contact with podiatry in a team approach context on diabetic foot ulcer and lower extremity amputation: systematic review and meta-analysis.Journal of foot and ankle research · 2020Pooled it
- Trial
- Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers: A Phase 3 Randomized Clinical Trial.JAMA network open · 2023Trial
- Immunoinflammatory Profile of FGF-18, IL-35 and Glutamic Acid Decarboxylase in Patients With Diabetic Foot Ulcers.International wound journal · 2026Article
- Functional and molecular insights in topical wound healing by ascorbic acid.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Two-year incidence and risk factors of diabetic foot ulcer: second phase report of Ahvaz diabetic foot cohort (ADFC) study.BMC endocrine disorders · 2024Article
- How does the clinical practice of Aotearoa New Zealand podiatrists align with international guidelines for the prevention of diabetes-related foot disease? A cross-sectional survey.Journal of foot and ankle research · 2023Article
- Amino acid analysis as a method of discovering biomarkers for diagnosis of diabetes and its complications.Amino acids · 2023Review
- Insoles to ease plantar pressure in people with diabetes and peripheral neuropathy: a feasibility randomised controlled trial with an embedded qualitative study.Pilot and feasibility studies · 2023Article
- Editorial: Pathogenesis of diabetic foot ulcers.Frontiers in pharmacology · 2023Article
- Etiology, Epidemiology, and Disparities in the Burden of Diabetic Foot Ulcers.Diabetes care · 2023Review
- [Factors Affecting the Surgical Level of Major Amputations in Patients with Severe Diabetic Foot].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022Article
- Article
- Diabetes-related lower extremity complications in a multi-ethnic Asian population: a 10 year observational study in Singapore.Diabetologia · 2021Observational
- The effects of dietary/herbal supplements and the serum levels of micronutrients on the healing of diabetic foot ulcers in animal and human models: a systematic review.Journal of diabetes and metabolic disorders · 2021Review
- Identifying major predictors of lower-extremity amputation in patients with diabetic foot ulcers.Journal of the Chinese Medical Association : JCMA · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo ascertain the effects of improvements in diabetic foot services over 18 years on incidence of diabetic foot ulceration. We also compared survival time from first ulcer development with presence of neuropathy, peripheral vascular disease, age and healing.
methodsPersons with new ulceration and those at high risk of ulcer development were referred to community podiatry from 1998. Their details were recorded, with verbal consent, on a central database. The effects of neuropathy, peripheral vascular disease, healing and age on survival were analysed by Cox proportional hazards ratios.
resultsThe incidence of first ulcer presentation decreased from 11.1 to 6.1 per 1000 persons between 2003 to 2017 (P <0.0001). Recurrent ulceration incidence remained stable. Prevalence of chronic and new foot ulceration combined increased from 20.7 to 33.1 per 1000 persons (P <0.0001). Ten-year survival was 85% for persons presenting with first ulcer and aged < 65 years, 50% for those aged 65-74 years and 25% for those aged 75-81 years (P < 0.0001). In those with peripheral vascular disease 5-year survival was 35% (P <0.001).
conclusionsIntegrated care for the diabetic foot in one National Health Service (NHS) health service area over 18 years was associated with a reduction in first presentations of diabetic foot ulceration, but failed to reduce recurrent ulceration. Cumulative prevalence of all ulcers continues to increase. Monitoring ulceration incidence can inform audit and planning of diabetic foot care services. Survival is better than reported previously in persons < 65 years and in the absence of peripheral vascular disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.