Evidence map›Paper›PMID 31150056›Full record

ArticleAmerican journal of hypertension2019

Effect of Arteriovenous Fistula Creation on Systolic and Diastolic Blood Pressure in Patients With Pre-dialysis Advanced Chronic Kidney Disease.

Roy O Mathew, Jerome Fleg, Janani Rangaswami, Bo Cai, Arif Asif, Mandeep S Sidhu, Sripal Bangalore

Open access · hybridAbstract readComparative StudyMulticenter Study
In one paragraph

Article in American journal of hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Advances in the Pathogenesis and Treatment of Resistant Hypertension.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Roy O MathewDivision of Nephrology, Department of Medicine, Columbia VA Health Care System, Columbia, South Carolina, USA.
Jerome FlegNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Janani RangaswamiDivision of Nephrology, Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania, USA.
Bo CaiDepartment of Epidemiology and Biostatistics, University of South Carolina Arnold School of Public Health, Columbia, South Carolina, USA.
Arif AsifDepartment of Medicine, Jersey Shore University Medical Center, Neptune, New Jersey, USA.
Mandeep S SidhuDivision of Cardiology, Department of Medicine, Albany Medical College, Albany, New York, USA.
Sripal BangaloreDivision of Cardiology, Department of Medicine, NYU Langone Medical Center, New York, New York, USA.
Albany Medical Center Hospital · USColumbia VA Health Care System · USEinstein Medical Center Philadelphia · USJersey Shore University Medical Center · USNational Institutes of Health · USNYU Langone Health · USUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral arteriovenous fistula (cAVF) has been investigated as a therapeutic measure for treatment-resistant hypertension in patients without advanced chronic kidney disease (CKD). There is considerable experience with the use of AVF for hemodialysis in patients with end-stage renal disease (ESRD). However, there is sparse data on the blood pressure (BP) effects of an AVF among patients with ESRD. We hypothesized that AVF creation would significantly reduce BP compared with patients who did not have an AVF among patients with ESRD before starting hemodialysis.

methodsBPs were compared during the 12 months before hemodialysis initiation in 399 patients with an AVF or AV graft created and 4,696 patients without either.

resultsAfter propensity score matching 1:2 ratio (AVF to no AVF), repeated measures analysis of variance revealed significant reductions of -1.7 mm Hg systolic and -3.9 mm Hg diastolic BP 12 months in patients after AVF creation; P = 0.025 and P < 0.001, respectively, compared with those with no AVF.

conclusionsThese findings suggest that AVF creation results in modest BP reduction in patients with pre-dialysis ESRD who require AVF for eventual hemodialysis therapy. Preferential diastolic BP reduction suggests that greater work is needed to characterize the ideal patient subset in which to use cAVF for treatment-resistant hypertension in those without advanced CKD.

Indexed as

Arteriovenous Shunt, SurgicalBlood PressureBlood Vessel Prosthesis ImplantationAgedAged, 80 and overAntihypertensive AgentsDatabases, FactualDiastoleFemaleHumansHypertensionKidney Failure, ChronicMaleMiddle AgedRenal DialysisRisk FactorsAntihypertensive Agentsarteriovenous fistulablood pressurecentral arteriovenous fistulachronic kidney diseasehypertensiontherapeuticstreatment-resistant hypertension

Identifiers

PMID31150056
PMCPMC6937624
OpenAlexW2946929257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.