Evidence map›Paper›PMID 31149806›Full record

ArticleACS nano2019

An

Huaxiao Yang, Xulei Qin, Huiyuan Wang, Xin Zhao, Yonggang Liu, Hung-Ta Wo, Chun Liu, Masataka Nishiga, Haodong Chen, Jing Ge and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS nano, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 139 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  9. Submucosal Hydrogel for Spring-Mediated Intestinal Lengthening.Journal of biomedical materials research. Part A · 2025
    Article
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  20. Non-Coding RNA-Targeted Therapy: A State-of-the-Art Review.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Huaxiao YangStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Xulei QinStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Huiyuan WangDepartment of Materials Science and Engineering , Stanford University , Stanford , California 94305 , United States.
Xin ZhaoStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Yonggang LiuStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Hung-Ta WoStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Chun LiuStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Masataka NishigaStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Haodong ChenStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Jing GeDepartment of Biomedical Engineering , Southern University of Science and Technology , Shenzhen , Guangdong 518055 , China.
Nazish SayedStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Oscar J AbilezStanford Cardiovascular Institute , Stanford University School of Medicine , Stanford , California 94305 , United States.
Dan DingState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences , Nankai University , Tianjin 300071 , China.ORCID 0000-0003-1873-6510
Sarah C HeilshornDepartment of Materials Science and Engineering , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0002-9801-6304
Kai LiDepartment of Biomedical Engineering , Southern University of Science and Technology , Shenzhen , Guangdong 518055 , China.ORCID 0000-0003-1664-5439
Cardiovascular Institute of the South · USSouthern University of Science and Technology · CNStanford University · USNankai University · CN

Funding

T32 Training Program in Mechanisms and Innovation in Vascular DiseaseT32HL098049 · NHLBI · STANFORD UNIVERSITY · PI Nicholas James Leeper, Philip S Tsao · 2010 to 2026
$6.3M
Engineered matrix microarrays to enhance the regenerative potential of iPSC-derived endothelial cellsR01HL142718 · NHLBI · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C, HUANG, NGAN F. · 2018 to 2021
$1.6M
Optogenetic Engineered Heart Muscle for Disease ModelingK01HL130608 · NHLBI · STANFORD UNIVERSITY · PI ABILEZ, OSCAR JOHN · 2016 to 2020
$862k
Engineered Protein Hydrogels to Modulate Adipose-derived Stromal Cell Secretome and Exosomes for Injectable Myocardial Infarction TherapyR21HL138042 · NHLBI · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C · 2017 to 2018
$435k
NHLBI NIH HHS K01 HL130608NHLBI NIH HHS L30 HL138771NHLBI NIH HHS R01 HL142718NHLBI NIH HHS R21 HL138042
6 · The paper itself

Abstract

A major challenge in myocardial infarction (MI)-related heart failure treatment using microRNA is the efficient and sustainable delivery of miRNAs into myocardium to achieve functional improvement through stimulation of intrinsic myocardial restoration. In this study, we established an

Indexed as

Gene Transfer TechniquesAnimalsCell DeathCell HypoxiaCell ProliferationGene Expression RegulationHuman Embryonic Stem CellsHumansHydrogelsInjectionsMicroRNAsMyocardial InfarctionMyocytes, CardiacNanoparticlesRatsReperfusion InjuryHydrogelsMicroRNAscardiovascular diseaseconjugated polymergene deliverymyocardial infarctionregenerative medicine

Identifiers

PMID31149806
PMCPMC7930012
OpenAlexW2947327480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.