ArticleThe Journal of nutrition2019
Dietary Patterns Are Not Consistently Associated with Variability in Blood Lead Concentrations in Pregnant British Women.
Article in The Journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Dietary and related data collected during pregnancy in the Avon Longitudinal Study of Parents and Children (ALSPAC).Wellcome open research · 2025Article
- Diet quality and blood lead levels in Uruguayan first graders.The Science of the total environment · 2024Article
- Automated lead toxicity prediction using computational modelling framework.Health information science and systems · 2023Article
- Trends of Blood Lead Levels in US Pregnant Women: The National Health and Nutrition Examination Survey (2001-2018).Frontiers in public health · 2022Article
- Prenatal Monitoring of Perinatal Pregnant Women and Fetus Based on a Smart Electronic Fetal Monitoring System.Journal of healthcare engineering · 2022Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundDuring pregnancy lead crosses the placenta freely and can have adverse effects on the fetus, with the potential for lifelong impact on the child. Identification of dietary patterns and food groups in relation to measures of lead status could provide a more useful alternative to nutrient-specific advice to minimize fetal lead exposure.
objectivesThe aim of this study was to evaluate whether dietary patterns and food groups are associated with blood lead concentration (B-Pb) in pregnancy.
designWhole blood samples were collected at a median of 11 wk gestation (IQR 9-13 wk) from women enrolled in the Avon Longitudinal Study of Parents and Children birth cohort study, and analyzed for lead. Dietary pattern scores were derived from principal components analysis of a food-frequency questionnaire (32 wk gestation). Associations of dietary pattern scores (quartiles), and of food groups (frequency of consumption), with the likelihood of B-Pb ≥5 µg/dL identified with adjusted logistic regression (n = 2167 complete cases).
resultsThere was a negative association between the "confectionery" dietary pattern and the likelihood of B-Pb ≥5 µg/dL (OR: 0.62; 95% CI: 0.41, 0.94) in an adjusted model. There were no associations with other dietary patterns. There was a positive association between the food group "all leafy green and green vegetables" and the likelihood of B-Pb ≥5 µg/dL (OR 1.45; 95% CI: 1.04, 2.01). Conversely, the food group "cakes and biscuits" was negatively associated (OR 0.63; 95% CI: 0.43, 0.93). After multiple imputation, there was a positive association of the "healthy" diet pattern and no association of the "confectionery" pattern.
conclusionsWe found limited evidence of an association between women's typical diet and B-Pb during pregnancy. Our findings do not indicate need to revise dietary guidance for pregnant women, who are advised to adopt a healthy diet in pregnancy, with a variety of foods consumed in moderation.
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