ArticleOptica2017
Chirped guided-mode resonance biosensor.
Article in Optica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 114 citations in OpenAlex.
- Multiplexed nanophotonic sensor arrays for time-resolved biomolecular analysis.Biosensors & bioelectronics · 2026Article
- Real-Time Acetone Gas Monitoring Using Calixarene-Functionalized Guided-Mode Resonance-Based Sensors.ACS photonics · 2026Article
- Highly sensitive refractive index sensor based on asymmetric spectral response of TiO2 high-contrast grating under LED illumination.PloS one · 2026Article
- Ultrasensitive Alzheimer's disease biomarker detection with nanopillar photonic crystal biosensors.Optica · 2025Article
- Beyond Spectral Resolution in Nanophotonic Sensing: Picometer-Level Precision with Multispectral Readout.ACS nano · 2025Article
- Nanophotonic sensing and label-free imaging of extracellular vesicles.Light, science & applications · 2025Review
- WSMicromachines · 2025Article
- Resonant Young's Slit Interferometer for Sensitive Detection of Low-Molecular-Weight Biomarkers.Biosensors · 2025Article
- Integrated Spectral Sensitivity as Physics-Based Figure of Merit for Spectral Transducers in Optical Sensing.Sensors (Basel, Switzerland) · 2025Article
- A passive blood separation sensing platform for point-of-care devices.Npj biosensing · 2025Article
- Noise Tolerant Photonic Bowtie Grating Environmental Sensor.ACS sensors · 2024Article
- On the reproducibility of electron-beam lithographic fabrication of photonic nanostructures.Scientific reports · 2024Article
- Article
- Handheld Biosensor System Based on a Gradient Grating Period Guided-Mode Resonance Device.Biosensors · 2023Article
- Rapid genetic screening with high quality factor metasurfaces.Nature communications · 2023Article
- Spatially Resolved Protein Binding Kinetics Analysis in Microfluidic Photonic Crystal Sensors.Sensors (Basel, Switzerland) · 2023Article
- Asymmetric tetramer metasurface sensor governed by quasi-bound states in the continuum.Nanophotonics (Berlin, Germany) · 2023Article
- Optical hydrogen sensing with high-Q guided-mode resonance of AlScientific reports · 2023Article
- Label-Free Bound-States-in-the-Continuum Biosensors.Biosensors · 2022Review
- Tunable guided resonance in twisted bilayer photonic crystal.Science advances · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advanced biomedical diagnostic technologies fulfill an important role in improving health and well-being in society. A large number of excellent technologies have already been introduced and have given rise to the "lab-on-a-chip" paradigm. Most of these technologies, however, require additional instrumentation for interfacing and readout, so they are often confined to the laboratory and are not suitable for use in the field or in wider clinical practice. Other technologies require a light coupling element, such as a grating coupler or a fiber coupler, which complicates packaging. Here, we introduce a novel biosensor based on a chirped guided-mode resonant grating. The chirped grating combines the sensing function with the readout function by translating spectral information into spatial information that is easily read out with a simple CMOS camera. We demonstrate a refractive index sensitivity of 137 nm/RIU and an extrapolated limit of detection of 267 pM for the specific binding of an immunoglobulin G antibody. The chirped guided-mode resonance approach introduces a new degree of freedom for sensing biomedical information that combines high sensitivity with autonomous operation. We estimate that the cost of components is U.S. $10 or less when mass manufactured, so the technology has the potential to truly transform point-of-care applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.