Evidence map›Paper›PMID 31149437›Full record

ArticleInternational cancer conference journal2016

Colon cancer chemotherapy for a patient with CDX2-expressing metastatic thymic adenocarcinoma: a case report and literature review.

Akihiko Sawaki, Mikiya Ishihara, Yuji Kozuka, Hiroyasu Oda, Satoshi Tamaru, Yumiko Sugawara, Yoshiki Yamashita, Toshiro Mizuno, Taizo Shiraishi, Naoyuki Katayama

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in International cancer conference journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Akihiko Sawaki1Department of Hematology and Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Mikiya Ishihara1Department of Hematology and Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Yuji Kozuka2Department of Pathology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Hiroyasu Oda1Department of Hematology and Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Satoshi Tamaru1Department of Hematology and Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Yumiko Sugawara1Department of Hematology and Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Yoshiki Yamashita1Department of Hematology and Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Toshiro Mizuno1Department of Hematology and Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Taizo Shiraishi2Department of Pathology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Naoyuki Katayama1Department of Hematology and Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507 Japan.
Mie University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 59-year-old man with thymic adenocarcinoma who was treated with colon cancer chemotherapy. He was referred to our hospital for an anterior mediastinal mass and multiple bone metastases that were found by computed tomography. Needle biopsy of the mediastinal tumor revealed a caudal-type homeobox 2 (CDX2)-positive adenocarcinoma. Neither upper nor lower gastrointestinal endoscopic examinations revealed any evidence of a primary tumor. The patient was administered CapeOX (capecitabine and oxaliplatin) and FOLFIRI (fluorouracil, leucovorin and irinotecan)/cetuximab. He died 6 months after diagnosis. Primary thymic adenocarcinoma was confirmed by autopsy. As far as we know, this is the first report in which colon cancer chemotherapy was used to treat CDX2-positive metastatic thymic adenocarcinoma.

Indexed as

CDX2ChemotherapyThymic adenocarcinoma

Identifiers

PMID31149437
PMCPMC6498364
OpenAlexW2195315939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.