Evidence map›Paper›PMID 31149297›Full record

ArticleActa endocrinologica (Bucharest, Romania : 2005)

ASSOCIATION OF THE HUMAN PPARγ2 PRO12ALA POLYMORPHISM WITH OBESITY IN A POPULATION FROM TURKEY.

M A Sözen, M U Özcan, M Çıldır, I H Doğru, A G Aygök, K Ü Balkan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Effects ofFrontiers in public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

M A SözenMed Biology, School of Medicine, Afyonkarahisar, Turkey.
M U ÖzcanAfyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
M ÇıldırAfyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
I H DoğruAfyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
A G AygökAfyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
K Ü BalkanAfyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
Maui Economic Development Board · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere have been a number of reports on the relationship between the PPARγ2 Pro12Ala genotype and the development of obesity.

objectiveA case-control survey was designed to investigate the potential association between a Pro12Ala polymorphism in the PPARγ2 gene and obesity and/or obesity-related phenotypes in a population from Turkey. MATERIALS AND

methodsThe polymerase chain reaction and restriction enzyme digestion were used to genotype the Pro12Ala polymorphism of the PPARγ2 gene in 149 unrelated obese and 105 non-obese control subjects from Turkey. The data were analyzed statistically.

resultsWe found that the overall minor allele frequency was 0.12 in cases and 0.095 in controls. In terms of genotype distribution and allele frequencies among the cases

conclusionOur results showed that the Pro12Ala polymorphism in the PPARγ2 gene is associated with obesity in the studied adult population from Turkey. These data suggest that the Pro12Ala polymorphism in PPARγ2 may be a potential genetic risk factor for central obesity.

Indexed as

central obesityobesitypolymorphismPPARγ2 genewaist-to-hip ratio

Identifiers

PMID31149297
PMCPMC6516403
OpenAlexW2913909867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.