Evidence map›Paper›PMID 31149229›Full record

ArticleActa endocrinologica (Bucharest, Romania : 2005)

CIRCULATING TUMOR CELLS IN MINIMALLY INVASIVE FOLLICULAR THYROID CARCINOMA AND BENIGN THYROID TUMORS WITH A FOLLICULAR PATTERN: PILOT EXPERIENCE.

C I Badulescu, R J Marlowe, A Piciu, R Buiga, O Barbos, N I Bejinariu, G Chereches, E Barbus, E A Bonci, D Piciu

Abstract read
In one paragraph

Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. CTC, ctDNA, and Exosome in Thyroid Cancers: A Review.International journal of molecular sciences · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

C I Badulescu"Prof.Dr.Ion Chiricuta" Institute of Oncology, Dept.of Surgical Oncology, Cluj-Napoca, Romania.
R J MarloweSpencer-Fontayne Corporation, New-Jersey, United States.
A Piciu"Prof.Dr.Ion Chiricuta" Institute of Oncology, Dept. of Medical Oncology, Cluj-Napoca, Romania.
R Buiga"Prof.Dr.Ion Chiricuta" Institute of Oncology, Dept. of Pathology, Cluj-Napoca, Romania.
O Barbos"Prof.Dr.Ion Chiricuta" Institute of Oncology, Dept. of Radiobiology and Tumor Biology, Cluj-Napoca, Romania.
N I BejinariuSantomar Oncodiagnostic, Cluj-Napoca, Romania.
G Chereches"Prof.Dr.Ion Chiricuta" Institute of Oncology, Dept. of Radiobiology and Tumor Biology, Cluj-Napoca, Romania.
E Barbus"Prof.Dr.Ion Chiricuta" Institute of Oncology, Dept of Nuclear Medicine, Cluj-Napoca, Romania.
E A Bonci"Prof.Dr.Ion Chiricuta" Institute of Oncology, Dept.of Surgical Oncology, Cluj-Napoca, Romania.
D Piciu"Prof.Dr.Ion Chiricuta" Institute of Oncology, Dept of Nuclear Medicine, Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMinimally invasive follicular thyroid carcinomas (MIFCs) are uncommon; literature offers limited guidance on their natural history and management. Starting January 2015 we measured circulating tumor cells (CTCs) in patients with MIFC (n=22) or benign thyroid tumors with follicular features (n=4).

methodsIn a retrospective analysis, we assessed detectability of and serial changes in CTC, compared demographic/clinical differences between CTC-positive

resultsThirteen patients (50%: 12/22 MIFC, 1/4 benign tumor) were initially CTC-positive; 3 remained CTC-positive in ≥1 subsequent measurement. CTC-positive patients had larger tumors and more frequent multifocality and vascular invasion

conclusionsIn the studied settings, CTC measurement is feasible, has unclear clinical/outcome implications, but may provide different information

Indexed as

circulating tumor cells (CTCs)differentiated thyroid carcinoma (DTC)minimally invasive follicular thyroid carcinoma (MIFC)risk stratification

Identifiers

PMID31149229
PMCPMC6516595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.