ArticleActa endocrinologica (Bucharest, Romania : 2005)
THE VOLUME OF SOLITARY PARATHYROID ADENOMA IS RELATED TO PREOPERATIVE PTH AND 25OH-D3, BUT NOT TO CALCIUM LEVELS.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 13 citations in OpenAlex.
- Comment to: Correlation between parathyroid adenoma volume and perioperative outcomes in primary hyperparathyroidism: does the size matter?Updates in surgery · 2026Article
- Correlation between preoperative biochemical indices and intraoperative findings in primary hyperparathyroidism.Gland surgery · 2026Article
- Correlation between parathyroid adenoma volume and perioperative outcomes in primary hyperparathyroidism: Does the size matter?Updates in surgery · 2025Article
- Predicting Tumor Volume in Primary Hyperparathyroidism From Preoperative Clinical Data.The Journal of clinical endocrinology and metabolism · 2025Article
- A new formula for predicting the actual volume of parathyroid adenoma in patients with primary hyperparathyroidism.Turkish journal of medical sciences · 2025Article
- Assessment of Vitamin D Status in Primary Hyperparathyroidism Patients: A Retrospective Study.Cureus · 2024Article
- Predicting ultrasound-guided thermal ablation benefit in primary hyperparathyroidism.European radiology · 2022Article
- Prospective Audit and Review of Parathyroid Surgery in Rural Setting.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Predictors of adenoma size and location in primary hyperparathyroidism.Langenbeck's archives of surgery · 2021Article
- MINIMALLY INVASIVE PARATHYROIDECTOMY FOR PRIMARY HYPERPARATHYROIDISM.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
10 authors at 1 institution in 1 country.
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Abstract
purposeTo correlate the volume of parathyroid adenomas with the hormonal and metabolic profile at patients diagnosed with primary hyperparathyroidism (pHPTH). PATIENTS AND
methodsCross-sectional multicentric study, enrolling 52 patients with pHPTH from two medical institutions. Serum calcium and PTH were evaluated in all patients before surgery, whereas 25OHD3 was measured only in the 33 patients recruited form one medical unit. The volume of parathyroid adenoma was measured by using the formula of a rotating ellipsoid.
resultsWe observed a significant correlation of the volume of parathyroid adenomas with PTH at patients from the two units and in the whole group (p < 0.0001), but not with serum calcium (p = 0.494). Twenty-five out of the 33 patients at whom 25OHD3 was measured had levels in the range of deficiency. 25OHD3 was not correlated with PTH or calcium levels, but was negatively correlated to the adenoma volume and positively to the PTH/volume ratio (p = 0.041 and p = 0.048, respectively).
conclusionsThe volume of parathyroid adenoma seems to be related to preoperative PTH and 25OHD3, but not to calcium level. Vitamin D deficiency is frequently found at patients with pHPTH and may contribute to particular disease profiles, including larger parathyroid adenomas.
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