Evidence map›Paper›PMID 31149192›Full record

ArticleActa endocrinologica (Bucharest, Romania : 2005)

ADIPONECTIN CORRELATION WITH BIOCLINICAL BENEFITS OF USING NATURAL THERAPEUTIC FACTORS IN KNEE OSTEOARTHRITIS.

E V Ionescu, I Tica, C Oprea, D M Iliescu, L C Petcu, M G Iliescu

Open access · greenAbstract read
In one paragraph

Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

E V IonescuBalneal and Rehabilitation Sanatorium of Techirghiol, "Ovidius" University of Constanta, Romania.
I TicaFaculty of Medicine - Medical Department, Constanta, Romania.
C OpreaBalneal and Rehabilitation Sanatorium of Techirghiol, "Ovidius" University of Constanta, Romania.
D M IliescuFaculty of Medicine - Medical Department, Constanta, Romania.
L C PetcuFaculty of Dentar Medicine - Departament of Biophysics, Biostatistics and Medical Informatics, Constanta, Romania.
M G IliescuDepartament of Rehabilitation Balneophysiokinetotherapy, Constanta, Romania.
Ovidius University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CONTEXT AND

objectiveThe new insights in the pathogenesis of osteoarthritis (OA) reveal the implications of adipocytokines. This study aims to analyze the correlations between the serum value of adiponectin and the clinical rehabilitation effects in patients diagnosed with knee OA, admitted and treated in the complex balneal resort of Techirghiol lake. SUBJECTS AND

methodsThe prospective randomized clinical study included 23 patients in the study group, diagnosed with knee OA according to ACR criteria, and a matching control group of 23 subjects. Serum level of adiponectin (using ELISA technique), uric acid, triglycerides, cholesterol, HDL-cholesterol and clinical response using a visual analog scale (VAS) were evaluated in all patients on their admission day and after 10 days of balneal treatment. Control group benefited from the same procedures except for cold mud therapy and mineral water baths.

resultsPlasma adiponectin levels (23.73±6.44 ng/dL) were statistically higher (p<0.05) in the study group compared to the control group (18.15±6.49 ng/dL). The mean VAS in both groups was decreased (p<0.005) compared to the initial moment.

conclusionsCold peloidotherapy combined with physical therapy and balneal factors induces serum adiponectin elevation and improves knee pain in OA. Therapeutic properties of Techirghiol mud still need further research.

Indexed as

adiponectinkneemudosteoarthritisTechirghiolVAS

Identifiers

PMID31149192
PMCPMC6516571
OpenAlexW2757642676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.