Evidence map›Paper›PMID 31149175›Full record

ReviewActa endocrinologica (Bucharest, Romania : 2005)

PREDICTIVE CIRCULATING MARKERS FOR ANTHRACYCLINE CHEMOTHERAPY IN NON-METASTATIC BREAST CANCER.

I Botnariuc, S M Ilie, O G Trifanescu, X E Bacinschi, F Curea, R M Anghel

Abstract readReview
In one paragraph

Review in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Observational
  3. A review of NTRK fusions in cancer.Annals of medicine and surgery (2012) · 2022
    Review
  4. Unexpected location of endometrial adenocarcinoma - a case report.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

I Botnariuc"Alexandru Trestioreanu" Institute of Oncology, Ringgold Standard Institution, Dept. of Radiotherapy, Bucharest, Romania.
S M Ilie"Alexandru Trestioreanu" Institute of Oncology, Ringgold Standard Institution, Dept. of Radiotherapy, Bucharest, Romania.
O G Trifanescu"Alexandru Trestioreanu" Institute of Oncology, Ringgold Standard Institution, Dept. of Radiotherapy, Bucharest, Romania.
X E Bacinschi"Alexandru Trestioreanu" Institute of Oncology, Ringgold Standard Institution, Dept. of Radiotherapy, Bucharest, Romania.
F Curea"Alexandru Trestioreanu" Institute of Oncology, Ringgold Standard Institution, Dept. of Radiotherapy, Bucharest, Romania.
R M Anghel"Alexandru Trestioreanu" Institute of Oncology, Ringgold Standard Institution, Dept. of Radiotherapy, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthracyclines are used in breast cancer both in early and advanced stages and their recommendation together with taxanes, either concurrently or sequentially, is debatable and individualized by phenotype. Circulating biomarkers have already been introduced in clinical practice for metastatic disease monitoring. We questioned whether it might be a role for these markers in neoadjuvant and adjuvant settings too and a general review was conducted. CK18 and CTC were found predictive for anthracycline related response in preoperative setting. Soluble E-cadherin is promising, a retrospective analysis showing a direct correlation with clinical response. CEA, CA 15-3 and HER2 ECD are not of interest for their predictive role.

Indexed as

anthracyclinesbreast cancercirculating biomarkers

Identifiers

PMID31149175
PMCPMC6516453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.