ArticleActa endocrinologica (Bucharest, Romania : 2005)
ASSOCIATION OF PANCREAS VOLUME AND INSULIN RESISTANCE WITH ABDOMINAL FAT DISTRIBUTION IN TYPE-2 DIABETES AS EVALUATED BY COMPUTED TOMOGRAPHY.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- An Investigation of the Relationship Between Pancreas Volume, Nutritional Status, and HbA1c in Geriatric Patients.Medicina (Kaunas, Lithuania) · 2025Article
- DXA-derived visceral adipose tissue reference values and metabolic syndrome risk threshold in an Algerian adult population.PloS one · 2025Article
- Visceral Adipose Tissue and Non-alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes.Digestive diseases and sciences · 2022Article
- 18F-FLUORODEOXYGLUCOSE PET/CT CAN BE AN ALTERNATIVE METHOD TO ASSESSMENT OF INSULIN RESISTANCE.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
purposeWe aimed to assess the relationship between the regional body fat distribution and insulin resistance and pancreas volume (PV) in type-2 diabetes (DM) patients.
methodsFifty-three consecutive type-2 diabetic and 51 non-diabetic patients matched by age, gender and body mass index (BMI) were enrolled. Subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), waist circumference, and PV were measured with computed tomography. Insulin resistance was assessed by the homeostasis model assessment of insulin resistance (HOMA-IR).
resultsPatients with type-2 DM had significantly lower PV than non-diabetic individuals. HOMA-IR ranged from 0.74 to 6.24; and from 0.37 to 3.26, in type-2 DM patients and non-diabetics, respectively. VAT was positively correlated with HOMA-IR in two groups. There were inverse correlations between PV and VAT and VAT/SAT but only in diabetics.
conclusionsThe VAT/SAT ratio may reflect the possible role of VAT to better understand the pathogenesis of obesity-related disorders in patients with type-2 DM.
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