ArticleActa endocrinologica (Bucharest, Romania : 2005)
VITAMIN DEFICIENCY AND INSULIN RESISTANCE IN NONDIABETIC OBESE PATIENTS.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 21 citations in OpenAlex.
- Gut microbiota profile in school-aged children with vitamin A depletion and vitamin E deficiency: A cross-sectional study.Gut microbes reports · 2027Article
- Vitamin BClinical nutrition ESPEN · 2025Observational
- Folate from probiotic bacteria and its therapeutic applications.Archives of microbiology · 2025Review
- Foundational Nutrition: Implications for Human Health.Nutrients · 2023Review
- Evaluation of the Relationship Between Smoking and Insulin Resistance: A Case-Control Study.Cureus · 2023Article
- Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals.International journal of environmental research and public health · 2022Article
- Relationship between Habitual Intake of Vitamins and New-Onset Prediabetes/Diabetes after Acute Pancreatitis.Nutrients · 2022Article
- The Relationship Between Folate, Vitamin B12 and Gestational Diabetes Mellitus With Proposed Mechanisms and Foetal Implications.Journal of family & reproductive health · 2021Review
- THE INVOLVEMENT OF VDR PROMOTER METHYLATION, CDX-2 VDR POLYMORPHISM AND VITAMIN D LEVELS IN MALE INFERTILITY.Acta endocrinologica (Bucharest, Romania : 2005)Article
- COVID-19 and obesity in childhood and adolescence: a clinical review.Jornal de pediatriaReview
- CORRELATIONS OF SERUM VITAMIN D WITH METABOLIC PARAMETERS IN ADULT OUTPATIENTS WITH DIFFERENT DEGREES OF OVERWEIGHT / OBESITY COMING FROM AN URBAN COMMUNITY.Acta endocrinologica (Bucharest, Romania : 2005)Article
- PREVENTION OF FALLS AND FRACTURES - TO "D" OR NOT TO "D"?Acta endocrinologica (Bucharest, Romania : 2005)Article
- VITAMIN D DEFICIENCY, A NONINVASIVE MARKER OF STEATOHEPATITIS IN PATIENTS WITH OBESITY AND BIOPSY PROVEN NONALCOHOLIC FATTY LIVER DISEASE.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveObese people may have nutritional deficiencies, although they are exposed to excessive food intake. We aim to assess relationship of vitamin D, B12, and folic acid levels and dietary vitamin intake and insulin resistance in obese people.
designThis case-control study was performed at the obesity outpatient clinics between March 2014 and April 2015. SUBJECTS AND
methodsWe included 304 non-diabetic obese subjects in patient group and 150 normal weight individuals in control group. Patients were questioned in detail about their food intake.
resultsMean age of obese patients was 37.3±10.1 years, the mean duration of obesity was 7.9±5.4 years, and the percentage of female patients was 65.8%. Mean vitamin D, B12, and folic acid levels were significantly lower in patients than in controls. Vitamin D deficiency (<20 ng/mL) in 69.7%, vitamin B12 deficiency (<200 pg/mL) in 13.5%, and folic acid deficiency (<4 ng/mL) was found in 14.2% of the patients. BMI negatively correlated with vitamin D, B12, and folic acid levels. B12 levels negatively correlated with duration of obesity. Insulin resistance was found in 55.9% of patients and HOMA-IR levels negatively correlated with vitamin D and B12 levels. While dietary vitamin D and folic acid intakes were inadequate in all of patients, only 28.3% of patients had inadequate vitamin B12 intake. There was no relation between vitamin levels and dietary vitamin intakes.
conclusionsThe study reveals that vitamin D, B12, and folic acid levels were low and poor vitamin D and B12 status were associated with insulin resistance in nondiabetic obese patients.
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