ArticleActa endocrinologica (Bucharest, Romania : 2005)
UPDATING THE CONCEPT OF METABOLICALLY HEALTHY OBESITY.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Abdominal Obesity Phenotypes and Incidence of Type 2 DM, Cardiovascular Outcomes and All-Cause Mortality-A Systematic Review and Meta-Analysis.Health science reports · 2026Review
- Comparison of gastric mucosa microbiota in metabolically healthy and unhealthy obesity.Diabetology & metabolic syndrome · 2025Article
- Metabolic Health, Overweight or Obesity, and Lung Function in Older Australian Adults.Nutrients · 2024Article
- Article
- Effect of oral cannabis administration on the fat depots of obese and streptozotocin-induced diabetic rats.Phytotherapy research : PTR · 2023Article
- The metabolic phenotype of the patient influences the reduction in carotid intima-media thickness achieved following metabolic surgery.The Journal of international medical research · 2022Article
- Causal relationship of excess body weight on cardiovascular events through risk factors.Scientific reports · 2022Article
- The Association Between Hyperuricemia and Obesity Metabolic Phenotypes in Chinese General Population: A Retrospective Analysis.Frontiers in nutrition · 2022Article
- Assessment of fatty liver and its correlation with glycemic control in patients with type 2 diabetes mellitus attending Dessie Comprehensive Specialized Hospital, Northeast Ethiopia.SAGE open medicine · 2022Article
- Data-driven identification of complex disease phenotypes.Journal of the Royal Society, Interface · 2021Article
- Identification of adipose tissue-related predictors of the reduction in cardiovascular risk induced by metabolic surgery.The Journal of international medical research · 2021Observational
- A Novel Subset of CD95Frontiers in immunology · 2020Article
- The Adipokine Profile and the Cardiometabolic Risk in Non-Obese Young AdultsBalkan medical journal · 2019Article
- Pharmacological management of non-alcoholic fatty liver disease: Atorvastatin versus pentoxifylline.Experimental and therapeutic medicine · 2017Article
- METABOLOMIC ANALYSIS OF NORMAL WEIGHT, HEALTHY AND UNHEALTHY OBESITY: AMINO ACID CHANGE ACROSS THE SPECTRUM OF METABOLIC WELLBEING IN WOMEN.Acta endocrinologica (Bucharest, Romania : 2005)Article
- HORMONAL REGULATION OF CARBOHYDRATE AND FAT METABOLISM IN WOMEN WITH DIFFERENT OBESITY TYPES IN THE FOOD DEPRIVATION TEST.Acta endocrinologica (Bucharest, Romania : 2005)Article
- TG/HDL-C RATIO AS CARDIO-METABOLIC BIOMARKER EVEN IN NORMAL WEIGHT WOMEN.Acta endocrinologica (Bucharest, Romania : 2005)Article
- THEActa endocrinologica (Bucharest, Romania : 2005)Article
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3 authors.
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Abstract
Obesity is a well-recognized risk factor for type 2 diabetes, cardiovascular disease, and several types of cancer. However, a proportion of the obese individuals display a significantly lower risk for metabolic complications than expected for their degree of body mass index, and this subtype of obesity was described as "metabolically healthy obesity" (MHO). No universally accepted criteria for the diagnosis of MHO exists and the prevalence of this subtype of obesity varies largely according to criteria used. Broadly, MHO is characterized by a lower amount of visceral fat, a more favorable inflammatory profile, and less insulin resistance as compared to the metabolically unhealthy obesity. Currently, controversies exist regarding the risk of cardiovascular events and all-cause mortality associated with MHO as compared to metabolically-healthy non-obese individuals. Further research is needed in order to identify the MHO phenotype and if MHO is truly healthy for a long period of time or if it is a transient state from normal metabolic/normal weight to abnormal metabolic/obese state. This review will discuss the MHO definition criteria; the differences between MHO and metabolically unhealthy obesity; the possible underlying mechanisms and clinical implications of MHO.
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