ArticleActa endocrinologica (Bucharest, Romania : 2005)
HYPOVITAMINOSIS D IN HIV-INFECTED PATIENTS.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 5 citations in OpenAlex.
- Association of 25(OH)D status with calcium metabolism, inflammation, and thyroid autoimmunity in patients with type 2 diabetes mellitus.Frontiers in endocrinology · 2026Article
- Potential pathogenic and protective genotypes and phenotypes of vitamin D binding protein in multiple sclerosis.Frontiers in neurology · 2025Article
- Article
- Consensus statement on the assessment of comorbidities in people living with HIV in Romania.Germs · 2019Review
- BONE QUALITY IN A YOUNG COHORT OF HIV-POSITIVE PATIENTS.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
5 authors at 1 institution in 3 countries.
Funding
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Abstract
introductionVitamin D (VD) deficiency is highly prevalent worldwide.
aimTo assess the prevalence of hypovitaminosis D in HIV-positive Romanian patients compared to controls.
methodsSerum 25OHD concentration was measured in HIV-infected patients and a control sample, matched by age, sex and menopausal status. The 25OHD status was defined as: deficiency < 20 ng/mL (severe deficiency <10 ng/mL), insufficiency 20-30 ng/mL, normal >30 ng/mL.
resultsWe evaluated 118 HIV-positive patients (72 males, 46 females), aged 36.9±12.2 years. 98.14% of them were on complex antiviral regimens. The B/C hepatitis coinfection rate was 9.3%. The control sample consisted of 119 subjects, (74 males, 45 women). The median and interquartile range for serum 25OHD concentration in patients was 17.6 (9.7, 26.9) ng/mL and 23.7 (18.4, 27.5) ng/mL in controls (p=0.001). Only 15.96% of HIV-positive cases and 12.71% of controls had normal VD status. The percentage of cases with severe VD deficiency was significantly higher in HIV positive cases (23.52%) compared to HIV-negative controls (4.2%, p=0.001).
conclusionsHypovitaminosis D was identified in 84.04% of HIV-infected patients, but the serum 25OHD concentration was not associated with specific HIV-related factors in our sample. Clinical guidelines regarding VD status determination and supplementation in HIV patients are needed.
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