ArticleTheranostics2019
Donation of mitochondria by iPSC-derived mesenchymal stem cells protects retinal ganglion cells against mitochondrial complex I defect-induced degeneration.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 115 citations in OpenAlex.
- Mitochondrial insufficiencies and neuroprotection in glaucoma.International ophthalmology · 2026Review
- Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Mitochondrial transfer and mesenchymal stem cells in ophthalmology: current evidence and therapeutic implications.Experimental biology and medicine (Maywood, N.J.) · 2026Review
- Clinical trials and advanced MRI techniques with stem cell therapy for ischemic stroke: present and future perspectives.Journal of translational medicine · 2025Review
- Mesenchymal stromal cell-mediated mitochondrial transfer unveils new frontiers in disease therapy.Stem cell research & therapy · 2025Review
- From powerhouse to modulator: regulating immune system responses through intracellular mitochondrial transfer.Cell communication and signaling : CCS · 2025Review
- Induced Mesenchymal Stem Cells: An Emerging Source for Regenerative Medicine Applications.Journal of clinical medicine · 2025Review
- MSCs act as biopatches for blood-retinal barrier preservation to enhance functional recovery after retinal I/R.Molecular therapy. Nucleic acids · 2025Article
- Engineered mitochondria in diseases: mechanisms, strategies, and applications.Signal transduction and targeted therapy · 2025Review
- Mesenchymal stem cells and mesenchymal stem cell-derived exosomes: a promising strategy for treating retinal degenerative diseases.Molecular medicine (Cambridge, Mass.) · 2025Review
- Human Pluripotent Stem Cell-Derived Alveolar Organoids for Gene-editing and Lung Adenocarcinomas Modeling.International journal of biological sciences · 2025Article
- Mitochondria Transfer in Mesenchymal Stem Cells: Unraveling the Mechanism and Therapeutic Potential.Current stem cell research & therapy · 2025Review
- Article
- Advances in mesenchymal stem cells and their derivatives for promoting peripheral nerve regeneration.Burns & trauma · 2025Review
- Stem Cell-Based Therapies for Glaucoma Treatment: A Review Bridging the Gap in Veterinary Patients.International journal of molecular sciences · 2024Review
- Induced pluripotent stem cell-derived mesenchymal stem cells: whether they can become new stars of cell therapy.Stem cell research & therapy · 2024Review
- Integrating Mitochondrial Biology into Innovative Cell Therapies for Neurodegenerative Diseases.Brain sciences · 2024Review
- Mitochondria in Retinal Ganglion Cells: Unraveling the Metabolic Nexus and Oxidative Stress.International journal of molecular sciences · 2024Review
- Mitochondrial transfer between BMSCs and Müller promotes mitochondrial fusion and suppresses gliosis in degenerative retina.iScience · 2024Article
- Horizontal mitochondrial transfer as a novel bioenergetic tool for mesenchymal stromal/stem cells: molecular mechanisms and therapeutic potential in a variety of diseases.Journal of translational medicine · 2024Review
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 6 institutions in 2 countries.
Dan JiangDepartment of Ophthalmology, The University of Hong Kong, Hong Kong SAR, P.R. China.
Guoyin XiongDepartment of Ophthalmology, The University of Hong Kong, Hong Kong SAR, P.R. China.
Hong FengDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Zhao ZhangGuangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, P.R. China.
Peikai ChenSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Bin YanSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Ling ChenDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Kesavamoorthy GandhervinDepartment of Ophthalmology, The University of Hong Kong, Hong Kong SAR, P.R. China.
Chuiyan MaDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Cheng LiDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Shuo HanDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Yuelin ZhangDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Can LiaoGuangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, P.R. China.
Tin-Lap LeeSchool of Biomedical Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong SAR, P.R. China.
Hung-Fat TseDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Qing-Ling FuOtorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P.R. China.
Kin ChiuDepartment of Ophthalmology, The University of Hong Kong, Hong Kong SAR, P.R. China.
Qizhou LianDepartment of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
University of Hong Kong · HKChinese University of Hong Kong · CNWenzhou Medical University · CNGuangzhou Medical University · CNAffiliated Eye Hospital of Wenzhou Medical College · CNSun Yat-sen University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsCell- and Tissue-Based TherapyDisease Models, AnimalElectron Transport Complex IElectroretinographyHumansInduced Pluripotent Stem CellsIntravitreal InjectionsMesenchymal Stem CellsMiceMice, KnockoutMitochondriaMitochondrial DiseasesRetinal Ganglion CellsTreatment OutcomeElectron Transport Complex Iinduced pluripotent stem cell derived-mesenchymal stem cellmitochondrial defectmitochondrial transferretinal ganglion cell
Identifiers
What OpenQuestion holds
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LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.