Evidence map›Paper›PMID 31149047›Full record

ArticleTheranostics2019

Biodistribution of gadolinium- and near infrared-labeled human umbilical cord mesenchymal stromal cell-derived exosomes in tumor bearing mice.

Javier Abello, Tuyen Duong Thanh Nguyen, Ramesh Marasini, Santosh Aryal, Mark Louis Weiss

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 1 synthesis or guideline pooled it, 138 citations in OpenAlex.

  1. Pooled it
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  15. Exosome tracking by magnetic resonance imaging.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Javier AbelloDepartment of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA.
Tuyen Duong Thanh NguyenDepartment of Chemistry, Kansas State University, Manhattan, KS 66506, USA.
Ramesh MarasiniDepartment of Chemistry, Kansas State University, Manhattan, KS 66506, USA.
Santosh AryalDepartment of Chemistry, Kansas State University, Manhattan, KS 66506, USA.
Mark Louis WeissDepartment of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA.
Kansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We speculate that exosomes derived from human umbilical cord mesenchymal stromal cells (HUC-MSCs) will accumulate within tumors and have the potential for both tumor location or drug delivery.

Indexed as

AnimalsCell Line, TumorCells, CulturedExosomesGadoliniumHumansInfrared RaysMagnetic Resonance ImagingMesenchymal Stem CellsMiceMice, NudeNanoparticlesOptical ImagingOsteosarcomaTissue DistributionUmbilical CordGadoliniumectopic osteosarcoma modelExtracellular vesiclesgadolinium nanoparticle.non-invasive imaging

Identifiers

PMID31149047
PMCPMC6531310
OpenAlexW2937014425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.