Evidence map›Paper›PMID 31149040›Full record

ArticleTheranostics2019

Soluble EMMPRIN levels discriminate aortic ectasia in Marfan syndrome patients.

Erica Rurali, Gianluca L Perrucci, Raffaella Gaetano, Alessandro Pini, Donato Moschetta, Davide Gentilini, Patrizia Nigro, Giulio Pompilio

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Soluble CD147 (BSG) as a Prognostic Marker in Multiple Myeloma.Current issues in molecular biology · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Erica RuraliVascular Biology and Regenerative Medicine Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Gianluca L PerrucciVascular Biology and Regenerative Medicine Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Raffaella GaetanoIstituto di Biomedicina ed Immunologia Molecolare "Alberto Monroy", CNR, Palermo, Italy.
Alessandro PiniRare Disease Center, Marfan Clinic, Cardiology department, ASST-FBF-Sacco, Milan, Italy.
Donato MoschettaVascular Biology and Regenerative Medicine Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Davide GentiliniMolecular Biology Laboratory, Unit of Bioinformatic and Statistical Genomic, Istituto Auxologico Italiano IRCCS, Cusano Milanino, Italy.
Patrizia NigroVascular Biology and Regenerative Medicine Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Giulio PompilioVascular Biology and Regenerative Medicine Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Centro Cardiologico Monzino · ITIRCCS Istituto Auxologico Italiano · ITIstituto di Biomedicina e di Immunologia Molecolare Alberto Monroy · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marfan syndrome (MFS) is a rare genetic disease characterized by a matrix metalloproteases (MMPs) dysregulation that leads to extracellular matrix degradation. Consequently, MFS patients are prone to develop progressive thoracic aortic enlargement and detrimental aneurysm. Since MMPs are activated by the extracellular MMP inducer (EMMPRIN) protein, we determined whether its plasmatic soluble form (sEMMPRIN) may be considered a marker of thoracic aortic ectasia (AE).

Indexed as

AdultAortaBasiginBiomarkersDilatation, PathologicFemaleHumansMaleMarfan SyndromeSensitivity and SpecificityBasiginBiomarkersBSG protein, humanaortic ectasiaEMMPRINMarfan syndromethoracic aortic aneurysmZ-score.

Identifiers

PMID31149040
PMCPMC6531292
OpenAlexW2938487374

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.