ArticleAfrican health sciences2019
Glyceryl trinitrate blocks staphyloxanthin and biofilm formation in
Article in African health sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
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- Plant Extract-Based Fabrication of Silver Nanoparticles and Their Effective Role in Antibacterial, Anticancer, and Water Treatment Applications.Plants (Basel, Switzerland) · 2023Article
- Diclofenac and Meloxicam Exhibited Anti-Virulence Activities Targeting Staphyloxanthin Production in Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023Article
- Synergistic Antibacterial Effect of Ethyl Acetate Fraction ofAdvances in pharmacological and pharmaceutical sciences · 2023Article
- Attenuating the virulence of the resistant superbug Staphylococcus aureus bacteria isolated from neonatal sepsis by ascorbic acid, dexamethasone, and sodium bicarbonate.BMC microbiology · 2022Article
- Novel silver metformin nano-structure to impede virulence of Staphylococcus aureus.AMB Express · 2022Article
- The promising anti-virulence activity of candesartan, domperidone, and miconazole on Staphylococcus aureus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Staphyloxanthin as a Potential Novel Target for Deciphering Promising Anti-Antibiotics (Basel, Switzerland) · 2022Review
- Promising FDA-approved drugs with efflux pump inhibitory activities against clinical isolates of Staphylococcus aureus.PloS one · 2022Article
- Impeding Virulence of Candida albicans by Candesartan and Domperidone.Current microbiology · 2021Article
- Virulence alterations in staphylococcus aureus upon treatment with the sub-inhibitory concentrations of antibiotics.Journal of advanced research · 2021Review
- NO donors and NO delivery methods for controlling biofilms in chronic lung infections.Applied microbiology and biotechnology · 2021Review
- In Vitro Antibacterial, Anti-Adhesive and Anti-Biofilm Activities ofAntibiotics (Basel, Switzerland) · 2021Article
- Genome-Wide Analysis ofFrontiers in microbiology · 2020Article
- Infections, NCDS, and the scourge of cyclones and Ebola in sub-Saharan Africa.African health sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background
objectivesInvestigation of the ability of glyceryl trinitrate (GTN) to inhibit staphyloxanthin, biofilm and tolerance to oxidative stress.
methodsThe disk sensitivity method was used to detect the methicillin resistance of
resultsGTN showed a significant inhibition of biofilm, staphyloxanthin and tolerance to oxidative stress. In the molecular docking study, it was found that GTN could bind to dehydrosqualene synthase enzyme by hydrogen bonding, electrostatic interaction and pi-cation interaction.
conclusionThe present study revealed the ability of GTN to serve as a potential anti-virulence candidate for attenuation of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.