Evidence map›Paper›PMID 31148833›Full record

ArticleCanadian oncology nursing journal = Revue canadienne de nursing oncologique2018

Potential mediators of improvement in painful chemotherapy-induced peripheral neuropathy via a web-based cognitive behavioural intervention.

Robert Knoerl, Debra L Barton, Janean E Holden, John C Krauss, Beth LaVasseur, Ellen M L Smith

Abstract read
In one paragraph

Article in Canadian oncology nursing journal = Revue canadienne de nursing oncologique, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The efficacy of web or mobile-based interventions to alleviate emotional symptoms in people with advanced cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert KnoerlPost-Doctoral Research Fellow, Phyllis F. Cantor, Center for Research in Nursing and Patient Care Services, Dana-Farber Cancer, Institute, 450 Brookline Avenue, LW 517, Boston, MA 02215, Email: Robert_knoerl@DFCI.Harvard.edu.
Debra L BartonMary Lou Willard French Professor of Nursing, University of Michigan School of Nursing, Ann Arbor, MI, Email: debbartn@umich.edu.
Janean E HoldenBarbara A. Therrien Collegiate Professor of Nursing, University of Michigan School of Nursing, Ann Arbor, MI, Email: holdenje@umich.edu.
John C KraussAssistant Professor, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, Email: jkrauss@med.umich.edu.
Beth LaVasseurDirector of Oncology Research and Operation, St. Joseph Mercy Hospital, Ann Arbor, MI, Email: beth.lavasseur@st.joeshealth.org.
Ellen M L SmithAssociate Professor, University of Michigan School of Nursing, Ann Arbor, MI, Email: ellenls@umich.edu.

Funding

Locus of Pain Control: Neural Substrates &ModifiabilityR01AR050044 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILLIAMS, DAVID A · 2004 to 2007
$2.1M
NIAMS NIH HHS R01 AR050044
6 · The paper itself

Abstract

purposePreliminary evidence suggests that a self-guided cognitive and behaviourally-based pain management intervention (PROSPECT) is effective for chronic painful chemotherapy-induced peripheral neuropathy (CIPN), but its mechanism of action is unknown. The purpose of this secondary analysis was to explore if changes in anxiety, depression, sleep-related impairment, or fatigue mediated improvements in worst pain following PROSPECT in individuals with chronic painful CIPN.

methodsSixty participants were randomized to receive self-guided cognitive behavioural pain management (access for eight weeks) or treatment as usual. A seven-day worst CIPN pain diary and the PROMIS measures of anxiety, depression, fatigue, and sleep-related impairment were administered pre/posttest (eight-weeks). Causal mediation analysis was used to quantify mediators of worst pain improvement.

resultsNone of the hypothesized mediators had a statistically significant effect on worst pain (n=38). IMPLICATIONS: Further research is needed to identify potential mediators of pain intensity that can be targeted by specific cognitive behavioural strategies to improve painful CIPN severity.

Indexed as

chemotherapy-induced peripheral neuropathychronic paincognitive behaviour therapyperipheral nervous system disease/chemically induced

Identifiers

PMID31148833
PMCPMC6516921

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.