Evidence map›Paper›PMID 31148526›Full record

ArticleParasitology2019

Genetic characterization of

Xiumin Han, Yingna Jian, Xueyong Zhang, Liqing Ma, Wenjun Zhu, Qigang Cai, Shile Wu, Xiangqian Wang, Bingqiang Shi

Open access · hybridAbstract read
In one paragraph

Article in Parasitology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Meta-Analysis of the Prevalence ofFrontiers in cellular and infection microbiology · 2021
    Pooled it
  3. Cattle as Biological Indicators ofAnimals : an open access journal from MDPI · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Parasitology · 2021
    Article
  12. Identification ofPathogens (Basel, Switzerland) · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiumin HanClinical Research Institute of Hydatid Disease, Qinghai Provincial People's Hospital, Xining 810007, China.
Yingna JianQinghai Academy of Animal Sciences and Veterinary Medicine, Qinghai University, State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining 810016, China.
Xueyong ZhangQinghai Academy of Animal Sciences and Veterinary Medicine, Qinghai University, State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining 810016, China.ORCID 0000-0001-5076-9211
Liqing MaQinghai Academy of Animal Sciences and Veterinary Medicine, Qinghai University, State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining 810016, China.
Wenjun ZhuClinical Research Institute of Hydatid Disease, Qinghai Provincial People's Hospital, Xining 810007, China.
Qigang CaiQinghai Academy of Animal Sciences and Veterinary Medicine, Qinghai University, State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining 810016, China.
Shile WuClinical Research Institute of Hydatid Disease, Qinghai Provincial People's Hospital, Xining 810007, China.
Xiangqian WangClinical Research Institute of Hydatid Disease, Qinghai Provincial People's Hospital, Xining 810007, China.
Bingqiang ShiClinical Research Institute of Hydatid Disease, Qinghai Provincial People's Hospital, Xining 810007, China.
Qinghai Provincial Peoples Hospital · CNQinghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined Echinococcus spp. genotypes and genetic variants isolated from humans as well as domestic and wild animals from the Qinghai-Tibetan Plateau Area using the cox1 gene. All samples except the pika isolates were identified as the Echinococcus granulosus sensu stricto. Sixteen different haplotypes with considerable intraspecific variation were detected and characterized in mitochondrial cox1 sequences. The parsimonious network of cox1 haplotypes showed star-like features, and the neutrality indexes computed via Tajima's D and Fu's Fs tests showed high negative values in E. granulosus s. s., indicating deviations from neutrality; the Fst values were low among the populations, implying that the populations were not genetically differentiated. The pika isolates were identified as E. multilocularis and E. shiquicus. Only one haplotype was recognized in the pika isolates. E. granulosus s. s. was the predominant species found in animals and humans, followed by E. multilocularis and E. shiquicus, with high genetic diversity circulating among the animals and humans in this area. Further studies are needed to cover many sample collection sites and larger numbers of pathogen isolates, which may reveal abundant strains and/or other haplotypes in the hydatid cysts infecting human and animal populations of the QTPA, China.

Indexed as

Genetic VariationGenotypeAnimalsAnimals, DomesticAnimals, WildChinaEchinococcosisEchinococcusElectron Transport Complex IVHaplotypesHumansElectron Transport Complex IVCox1 genegenetic variationgenotypehaplotypeshydatid cystQinghai-Tibetan Plateau Area

Identifiers

PMID31148526
PMCPMC6700708
OpenAlexW2947231111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.