Evidence map›Paper›PMID 31148524›Full record

ArticleEpigenetics2019

DNA methylation patterns in human iPSC-derived sensory neuronal differentiation.

Soneela Ankam, Amandine Rovini, Saurabh Baheti, Ron Hrstka, Yanhong Wu, Kiley Schmidt, Hailong Wang, Nicolas Madigan, Lena-Sophie Koenig, Kimberly Stelzig and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  5. Review
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  10. METTL1-mediated mStem cell research & therapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Soneela Ankama Department of Neurology, Mayo Clinic , Rochester , MN , USA.ORCID 0000-0003-3576-9082
Amandine Rovinia Department of Neurology, Mayo Clinic , Rochester , MN , USA.
Saurabh Bahetib Division of Biomedical Statistics and Informatics, Mayo Clinic , Rochester , MN , USA.
Ron Hrstkaa Department of Neurology, Mayo Clinic , Rochester , MN , USA.
Yanhong Wuc Department of Laboratory Medicine and Pathology, Mayo Clinic , Rochester , MN , USA.
Kiley Schmidta Department of Neurology, Mayo Clinic , Rochester , MN , USA.
Hailong Wanga Department of Neurology, Mayo Clinic , Rochester , MN , USA.
Nicolas Madigana Department of Neurology, Mayo Clinic , Rochester , MN , USA.
Lena-Sophie Koeniga Department of Neurology, Mayo Clinic , Rochester , MN , USA.
Kimberly Stelzigd Center for Regenerative Medicine Biotrust, Mayo Clinic , Rochester , MN , USA.
Zachary Reschd Center for Regenerative Medicine Biotrust, Mayo Clinic , Rochester , MN , USA.
Christopher J Kleina Department of Neurology, Mayo Clinic , Rochester , MN , USA.
Zhifu Sunb Division of Biomedical Statistics and Informatics, Mayo Clinic , Rochester , MN , USA.
Nathan P Staffa Department of Neurology, Mayo Clinic , Rochester , MN , USA.ORCID 0000-0001-6760-3859
Mayo Clinic in Arizona · USMayo Clinic · US

Funding

Assessment of Chemotherapy-Induced Peripheral Neuropathy Susceptibility Using Patient-derived iPSC TechnologyR01CA211887 · NCI · MAYO CLINIC ROCHESTER · PI STAFF, NATHAN P · 2017 to 2021
$1.8M
Mechanisms of Bortezomib-induced Peripheral NeuropathyK08CA169443 · NCI · MAYO CLINIC ROCHESTER · PI STAFF, NATHAN P · 2012 to 2016
$722k
NCI NIH HHS K08 CA169443NCI NIH HHS R01 CA211887
6 · The paper itself

Abstract

Sensory neurons of the peripheral nervous system are critical in health and disease. Sensory neurons derived from induced pluripotent stem (iPS) cells are now being used increasingly for

Indexed as

DNA MethylationAgedCell DifferentiationCells, CulturedCpG IslandsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BDown-RegulationEpigenomicsFemaleHumansInduced Pluripotent Stem CellsPhenotypeSensory Receptor CellsWhole Genome SequencingYoung AdultDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BdifferentiationDNA methylationiPSCsensory neuron

Identifiers

PMID31148524
PMCPMC6691994
OpenAlexW2947290472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.