Evidence map›Paper›PMID 31148000›Full record

ArticleEnvironmental science and pollution research international2019

Redox status and fatty acid composition of Mactra corallina digestive gland following exposure to acrylamide.

Wafa Trabelsi, Imene Chetoui, Chaima Fouzai, Safa Bejaoui, Imen Rabeh, Khaoula Telahigue, Mohamed Chalghaf, Mhamed El Cafsi, Nejla Soudani

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In one paragraph

Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wafa TrabelsiLaboratory of Ecology, Biology and Physiology of Aquatic Organisms, Department of Biology, Tunis Faculty of Sciences, University of Tunis El Manar, 2092, Tunis, Tunisia. wafa.trabelsi@etudiant-fst.utm.tn.ORCID http://orcid.org/0000-0002-1114-4080
Imene ChetouiLaboratory of Ecology, Biology and Physiology of Aquatic Organisms, Department of Biology, Tunis Faculty of Sciences, University of Tunis El Manar, 2092, Tunis, Tunisia.
Chaima FouzaiLaboratory of Ecology, Biology and Physiology of Aquatic Organisms, Department of Biology, Tunis Faculty of Sciences, University of Tunis El Manar, 2092, Tunis, Tunisia.
Safa BejaouiLaboratory of Ecology, Biology and Physiology of Aquatic Organisms, Department of Biology, Tunis Faculty of Sciences, University of Tunis El Manar, 2092, Tunis, Tunisia.
Imen RabehLaboratory of Ecology, Biology and Physiology of Aquatic Organisms, Department of Biology, Tunis Faculty of Sciences, University of Tunis El Manar, 2092, Tunis, Tunisia.
Khaoula TelahigueLaboratory of Ecology, Biology and Physiology of Aquatic Organisms, Department of Biology, Tunis Faculty of Sciences, University of Tunis El Manar, 2092, Tunis, Tunisia.
Mohamed ChalghafAquatic Environment Exploitation Resources Unit, Higher Institute Fishing and Fish Farming of Bizerte, Bizerte, Tunisia.
Mhamed El CafsiLaboratory of Ecology, Biology and Physiology of Aquatic Organisms, Department of Biology, Tunis Faculty of Sciences, University of Tunis El Manar, 2092, Tunis, Tunisia.
Nejla SoudaniLaboratory of Ecology, Biology and Physiology of Aquatic Organisms, Department of Biology, Tunis Faculty of Sciences, University of Tunis El Manar, 2092, Tunis, Tunisia.
Tunis El Manar University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acrylamide (ACR), a ubiquitous agent, has various chemical and industrial applications, and it is found in backed or fried carbohydrate-rich food. It has been related to multiple toxicological effects, and it causes high cytotoxicity through oxidative stress. The present study aimed to investigate the potential effect of ACR toxicity administered at different concentrations (5, 10, and 20 mg/L), during 5 days, in order to evaluate the fatty acid (FA) composition and redox state in the digestive gland of Mactra corallina. The results showed, in ACR-treated clams, a significant increase in malondialdehyde, hydrogen peroxide, protein carbonyl, and metallothionein levels, as well as an alteration of the enzymatic (superoxide dismutase, glutathione peroxidase, and catalase) and non-enzymatic (reduced glutathione and ascorbic acid) antioxidant status. However, acetylcholinesterase activity was inhibited in a concentration-dependent manner. In our experiment, the n-3 (Omega-3) and n-6 (Omega-6) polyunsaturated fatty acid levels were significantly changed in all ACR-treated groups. A decrease in eicosapentaenoic acid (C20:5n-3, EPA) and docosahexaenoic acid (C22:6n-3, DHA) was observed in 10-mg/L and 20-mg/L ACR-treated groups. Nevertheless, arachidonic acid (C20:4n-6, ARA) and its precursor linoleic acid (C18:2n-6, LA) were increased. Besides oxidative stress parameters, FA composition may be an additional tool for assessing ACR contamination.

Indexed as

AcrylamideAnimalsAntioxidantsArachidonic AcidBivalviaCatalaseDigestionDocosahexaenoic AcidsEicosapentaenoic AcidFatty AcidsFatty Acids, Omega-3GlutathioneLinoleic AcidOxidation-ReductionOxidative StressSuperoxide DismutaseAcrylamideAntioxidantsArachidonic AcidCatalaseDocosahexaenoic AcidsEicosapentaenoic Acideicosapentaenoic acid ethyl esterFatty AcidsFatty Acids, Omega-3GlutathioneLinoleic AcidSuperoxide DismutaseAcrylamideAntioxidant statusDigestive glandExposureFatty acidsMactra corallinaOxidative stress

Identifiers

PMID31148000
OpenAlexW2946918485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.