Evidence map›Paper›PMID 31147885›Full record

ArticleAdvances in experimental medicine and biology2019

Pericytes in Muscular Dystrophies.

Louise Anne Moyle, Francesco Saverio Tedesco, Sara Benedetti

Open access · greenAbstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Pericytes in the optic nerve head.Progress in retinal and eye research · 2025
    Review
  4. MuSCs and IPCs: roles in skeletal muscle homeostasis, aging and injury.Cellular and molecular life sciences : CMLS · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Arsenic Directs Stem Cell Fate by Imparting Notch Signaling Into the Extracellular Matrix Niche.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
  9. Next Stage Approach to Tissue Engineering Skeletal Muscle.Bioengineering (Basel, Switzerland) · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Louise Anne MoyleInstitute of Biomaterials and Biomedical Engineering, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Francesco Saverio TedescoDepartment of Cell and Developmental Biology, University College London, London, UK. f.s.tedesco@ucl.ac.uk.
Sara BenedettiGreat Ormond Street Institute of Child Health, University College London, London, UK. s.benedetti@ucl.ac.uk.
Great Ormond Street Hospital · GBUniversity College London · GBUniversity of Toronto · CA

Funding

EPA EP-D-18-001European Research Council 759108
6 · The paper itself

Abstract

The muscular dystrophies are an heterogeneous group of inherited myopathies characterised by the progressive wasting of skeletal muscle tissue. Pericytes have been shown to make muscle in vitro and to contribute to skeletal muscle regeneration in several animal models, although recent data has shown this to be controversial. In fact, some pericyte subpopulations have been shown to contribute to fibrosis and adipose deposition in muscle. In this chapter, we explore the identity and the multifaceted role of pericytes in dystrophic muscle, potential therapeutic applications and the current need to overcome the hurdles of characterisation (both to identify pericyte subpopulations and track cell fate), to prevent deleterious differentiation towards myogenic-inhibiting subpopulations, and to improve cell proliferation and engraftment efficacy.

Indexed as

Muscular DystrophiesPericytesAnimalsCell DifferentiationMuscle DevelopmentMuscle, SkeletalRegenerationAdipogenesisCell therapyChondrogenesisFibrosisMuscleMuscle regenerationMuscular dystrophyPericytesPlasticityStem cells

Identifiers

PMID31147885
PMCPMC7611401
OpenAlexW2947660851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.