SynthesisInfection2019
Worldwide literature on epidemiology of human alveolar echinococcosis: a systematic review of research published in the twenty-first century.
Synthesis in Infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 67 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- MicroRNAs during Echinococcus spp. infection: a comprehensive systematic review and implications for diagnosis and therapy.Parasites & vectors · 2026Pooled it
- Risk Factors Associated With Echinococcosis in the General Chinese Population: A Meta-Analysis and Systematic Review.Frontiers in public health · 2022Pooled it
- Accession-level reassessment of cox1 identity in the first Korean case of Echinococcus multilocularis.Parasites, hosts and diseases · 2026Article
- Present Situation of Cystic Echinococcosis in Africa: A Narrative Review.Veterinary sciences · 2026Review
- Unmasking the mimic: vertebral alveolar echinococcosis diagnosed by metagenomic next-generation sequencing.Infection · 2026Article
- CCR8 orchestrates an immunosuppressive niche in the liver to promote Echinococcus multilocularis infection.PLoS neglected tropical diseases · 2026Article
- Diagnosis of hepatic alveolar echinococcosis:18F-FDG-PET activity compared to the Echinococcus multilocularis Ulm Ultrasound Classification.Nuklearmedizin. Nuclear medicine · 2026Article
- A retrospective study on the efficacy of ex vivo liver resection combined with autologous liver transplantation in treating advanced alveolar echinococcosis at high altitude.BMC gastroenterology · 2025Article
- Sonographic double patterns in hepatic alveolar echinococcosis according to the echinococcosis multilocularis ultrasound classification.Parasitology research · 2025Article
- The Effect of Climate Change on Emergence and Evolution of Zoonotic Diseases in Asia.Zoonoses and public health · 2025Review
- The initial stage of alveolar echinococcosis is a diagnostic challenge: a case report.Journal of medical case reports · 2025Article
- The value of nomogram analysis in predicting pulmonary metastasis in hepatic alveolar echinococcosis.Scientific reports · 2025Article
- Pulmonary manifestations and clinical management of echinococcosis in a low-endemic region of Mexico: a 15-year retrospective cohort study at a tertiary hospital.Tropical medicine and health · 2025Article
- CT-based radiomics models using intralesional and different perilesional signatures in predicting the microvascular density of hepatic alveolar echinococcosis.BMC medical imaging · 2025Article
- Expression of TNF-α, VEGF-A and Microvessel Density in Cerebral Alveolar Echinococcosis and Their Correlation with Perilesional Brain Edema.Acta parasitologica · 2025Article
- CD155 as a therapeutic target in alveolar echinococcosis: insights from anFrontiers in microbiology · 2025Article
- Ex vivo Liver Autotransplantation for Alveolar Echinococcosis with Brain and Lung Metastases: A Case Report.International medical case reports journal · 2025Article
- Dog deworming by smart collar: a 24-month field evaluation from a One Health prospective, randomized, double masked trial.Science in One Health · 2025Article
- Article
- A Case Series and Literature Review of Alveolar Echinococcosis in Kashmir, India: An Emerging Endemic Zone forLife (Basel, Switzerland) · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeHuman alveolar echinococcosis (AE) is a potentially lethal zoonosis caused by the cestode Echinococcus multilocularis. The aim of this systematic review is to establish a comprehensive global AE literature overview taking into account the epidemiologically relevant AE research of the twenty-first century.
methodsWe systematically searched the global literature published from 2001 through 2018 via MEDLINE, EMBASE, the Russian databases eLIBRARY.RU, CyberLeninka, the Chinese databases CNKI, VIP, Journals. RESEARCH: ac.ir (Farsi language-based), Jordan E-Library (Arab language-based) and supplementary Google Scholar, in accordance with the PRISMA guidelines. QGIS software was used for the mapping of the affected countries.
resultsWe have listed 154 relevant publications in the final literature synopsis in consideration of our quality assessment. Including non-autochthonous cases, human AE was reported in 36 countries within the northern hemisphere from 2001 to 2018. The first publication of AE in Tajikistan, Pakistan, South Korea, Belgium, the Netherlands, Slovakia, Hungary, Lithuania, Latvia, Slovenia and Morocco occurred in this century; further first cases in Taiwan, Thailand, and Denmark were considered to be non-autochthonous by the authors. The highest total case numbers (n ≥ 100 in a single article) were reported in France, Germany, Switzerland, Poland, and Lithuania, including China and Kyrgyzstan with by far the highest prevalence figures.
conclusionsOur paper emphasises the increasing spread of reported cases and the rise in its numbers in the literature of the twenty-first century, especially in western, northern and eastern Europe, as well as in central Asia. Epidemiological studies on human infections are lacking in many parts of the world.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.