Evidence map›Paper›PMID 31147782›Full record

ArticleMedical microbiology and immunology2019

Influence of Hepatitis C virus coinfection on immune reconstitution in HIV subjects.

María Noel Badano, Cecilia Parodi, Natalia Aloisi, Marcelo Corti, María Marta Elizalde de Bracco, Patricia Baré

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In one paragraph

Article in Medical microbiology and immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Decreased Activated CD4Viral immunology · 2021
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María Noel BadanoLaboratory of Immunology, Instituto de Medicina Experimental (IMEX)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Academia Nacional de Medicina, J.A. Pacheco de Melo 3081, CABA 1425, Buenos Aires, Argentina. noebadano@yahoo.com.ar.ORCID http://orcid.org/0000-0002-0358-7738
Cecilia ParodiLaboratory of Immunology, Instituto de Medicina Experimental (IMEX)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Academia Nacional de Medicina, J.A. Pacheco de Melo 3081, CABA 1425, Buenos Aires, Argentina.
Natalia AloisiLaboratory of Immunology, Instituto de Medicina Experimental (IMEX)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Academia Nacional de Medicina, J.A. Pacheco de Melo 3081, CABA 1425, Buenos Aires, Argentina.
Marcelo CortiFundación de la Hemofilia, Soler 3483, CABA 1174, Buenos Aires, Argentina.
María Marta Elizalde de BraccoLaboratory of Immunology, Instituto de Medicina Experimental (IMEX)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Academia Nacional de Medicina, J.A. Pacheco de Melo 3081, CABA 1425, Buenos Aires, Argentina.
Patricia BaréLaboratory of Immunology, Instituto de Medicina Experimental (IMEX)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Academia Nacional de Medicina, J.A. Pacheco de Melo 3081, CABA 1425, Buenos Aires, Argentina.

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas PIP 11220120100619CO
6 · The paper itself

Abstract

Despite successful HIV suppression by antiretroviral treatment (ART), immune activation may persist in HIV patients, contributing to an impaired immunological reconstitution and disease progression. Information regarding Hepatitis C virus (HCV) coinfection as a factor that accounts for immune activation in HIV subjects remains unclear. Furthermore, most studies have been carried out considering HIV/HCV patients as a whole, without taking into account the presence or absence of liver damage. Therefore, it is unknown if HCV and/or its liver-related disease could act as two independent factors contributing to the immune activation. In this study, we investigated the presence of immune activation in a cohort of 50 HIV/HCV patients by measuring cytokine levels, CD4

Indexed as

Immune ReconstitutionAdolescentAdultAgedAnti-Retroviral AgentsCD4-CD8 RatioCD4 Lymphocyte CountCoinfectionCross-Sectional StudiesCytokinesHepatitis CHIVHIV InfectionsHumansLongitudinal StudiesMaleAnti-Retroviral AgentsCytokinesAntiretroviral treatmentHIV/HCV coinfectionImmune activationImmunological reconstitutionLiver disease

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.