Evidence map›Paper›PMID 31147736›Full record

ReviewCurrent genetics2019

Unravelling nuclear size control.

Helena Cantwell, Paul Nurse

Abstract readReview
In one paragraph

Review in Current genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Differential sensitivity of midline development to mitosis during and after primitive streak extension.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Morphological specializations of mosquito COProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Micro-Scale Topography Triggers Dynamic 3D Nuclear Deformations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Helena CantwellCell Cycle Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. helena.cantwell@berkeley.edu.ORCID http://orcid.org/0000-0002-7714-995X
Paul NurseCell Cycle Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.ORCID http://orcid.org/0000-0002-9244-7787

Funding

The Francis Crick Institute FC01121Wellcome Trust 093917Wellcome Trust FC001121
6 · The paper itself

Abstract

Correlation between nuclear and cell size, the nucleocytoplasmic ratio, is a cellular phenomenon that has been reported throughout eukaryotes for more than a century but the mechanisms that achieve it are not well understood. Here, we review work that has shed light on the cellular processes involved in nuclear size control. These studies have implicated nucleocytoplasmic transport, LINC complexes, RNA processing, regulation of nuclear envelope expansion and partitioning of importin α in nuclear size control, moving us closer to a mechanistic understanding of this phenomenon.

Indexed as

Active Transport, Cell NucleusAnimalsCell NucleusCell Nucleus SizeCytoplasmHumansNuclear EnvelopeNuclear MatrixRNA, Long NoncodingRNA, MessengerSchizosaccharomycesRNA, Long NoncodingRNA, MessengerFission yeastIntracellular scalingNuclear envelopeNucleocytoplasmic transportNucleusOrganellesSize control

Identifiers

PMID31147736
PMCPMC6820586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.