Evidence map›Paper›PMID 31147707›Full record

ArticleNucleic acids research2019

LnCompare: gene set feature analysis for human long non-coding RNAs.

Joana Carlevaro-Fita, Leibo Liu, Yuan Zhou, Shan Zhang, Panagiotis Chouvardas, Rory Johnson, Jianwei Li

Abstract read
In one paragraph

Article in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. lncHUB2: aggregated and inferred knowledge about human and mouse lncRNAs.Database : the journal of biological databases and curation · 2023
    Article
  4. Review
  5. Review
  6. Article
  7. Parsing the role of NSP1 in SARS-CoV-2 infection.bioRxiv : the preprint server for biology · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Annotation and curation of the causality information in LncRNADisease.Database : the journal of biological databases and curation · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joana Carlevaro-FitaDepartment of BioMedical Research (DBMR), University of Bern, Bern 3008, Switzerland.
Leibo LiuInstitute of Computational Medicine, School of Artificial Intelligence, Hebei University of Technology, Tianjin 300401, China.
Yuan ZhouDepartment of Biomedical Informatics, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Shan ZhangInstitute of Computational Medicine, School of Artificial Intelligence, Hebei University of Technology, Tianjin 300401, China.
Panagiotis ChouvardasDepartment of BioMedical Research (DBMR), University of Bern, Bern 3008, Switzerland.
Rory JohnsonDepartment of BioMedical Research (DBMR), University of Bern, Bern 3008, Switzerland.
Jianwei LiInstitute of Computational Medicine, School of Artificial Intelligence, Hebei University of Technology, Tianjin 300401, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interest in the biological roles of long noncoding RNAs (lncRNAs) has resulted in growing numbers of studies that produce large sets of candidate genes, for example, differentially expressed between two conditions. For sets of protein-coding genes, ontology and pathway analyses are powerful tools for generating new insights from statistical enrichment of gene features. Here we present the LnCompare web server, an equivalent resource for studying the properties of lncRNA gene sets. The Gene Set Feature Comparison mode tests for enrichment amongst a panel of quantitative and categorical features, spanning gene structure, evolutionary conservation, expression, subcellular localization, repetitive sequences and disease association. Moreover, in Similar Gene Identification mode, users may identify other lncRNAs by similarity across a defined range of features. Comprehensive results may be downloaded in tabular and graphical formats, in addition to the entire feature resource. LnCompare will empower researchers to extract useful hypotheses and candidates from lncRNA gene sets.

Indexed as

SoftwareGenesGenes, NeoplasmHumansRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID31147707
PMCPMC6602513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.