Evidence map›Paper›PMID 31147684›Full record

ArticleJournal of radiation research2019

Impact of delivery characteristics on dose delivery accuracy of volumetric modulated arc therapy for different treatment sites.

Jiaqi Li, Xile Zhang, Jun Li, Rongtao Jiang, Jing Sui, Maria F Chan, Ruijie Yang

Abstract read
In one paragraph

Article in Journal of radiation research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. A comprehensive site-specific analysis of patient-specific quality assurance based on dose volume histogram of RapidArc treatment delivery.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Integration of AI and Machine Learning in Radiotherapy QA.Frontiers in artificial intelligence · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiaqi LiDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Xile ZhangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Jun LiDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Rongtao JiangBrainnetome Center & National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
Jing SuiBrainnetome Center & National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
Maria F ChanMedical Physics Department, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ruijie YangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

This study aimed to investigate the impact of delivery characteristics on the dose delivery accuracy of volumetric modulated arc therapy (VMAT) for different treatment sites. The pretreatment quality assurance (QA) results of 344 VMAT patients diagnosed with gynecological (GYN), head and neck (H&N), rectal or prostate cancer were randomly chosen in this study. Ten metrics reflecting VMAT delivery characteristics were extracted from the QA plans. Compared with GYN and rectal plans, H&N and prostate plans had higher aperture complexity and monitor units (MU), and smaller aperture area. Prostate plans had the smallest aperture area and lowest leaf speed compared with other plans (P < 0.001). No differences in gantry speed were found among the four sites. The gamma passing rates (GPRs) of GYN, rectal and H&N plans were inversely associated with union aperture area (UAA) and leaf speed (Pearson's r: -0.39 to -0.68). GPRs of prostate plans were inversely correlated with aperture complexity, MU and small aperture score (SAS) (absolute Pearson's r: 0.34 to 0.49). Significant differences in GPR between high SAS and low SAS subgroups were found only when leaf speed was <0.42 cm s-1 (P < 0.001). No association of GPR with gantry speed was found in four sites. Leaf speed was more strongly associated with UAA. Aperture complexity and MU were more strongly associated with SAS. VMAT plans from different sites have distinct delivery characteristics. Affecting dose delivery accuracy, leaf speed is the key factor for GYN, rectal and H&N plans, while aperture complexity, MU and small apertures have a higher influence on prostate plans.

Indexed as

Radiotherapy, Intensity-ModulatedDose-Response Relationship, RadiationHumansMaleProstatic NeoplasmsRectal Neoplasmscomplexity metricsgamma passing ratequality assurancevolumetric modulated arc therapy

Identifiers

PMID31147684
PMCPMC6805974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.