Evidence map›Paper›PMID 31147611›Full record

ArticleScientific reports2019

Female-specific decreases in alcohol binge-like drinking resulting from GABA

L M Darnieder, L C Melón, T Do, N L Walton, K A Miczek, J L Maguire

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Allosteric modulators of the δ GABANeuropharmacology · 2022
    Article
  5. Article
  6. Article
  7. Neurobiological Bases of Alcohol Consumption After Social Stress.Current topics in behavioral neurosciences · 2022
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

L M DarniederGraduate Program in Neuroscience, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, 02111, USA.
L C MelónTufts University School of Medicine, Department of Neuroscience, Boston, MA, 02111, USA.ORCID http://orcid.org/0000-0002-2256-3707
T DoNortheastern University, Bouvé College of Health Sciences, Boston, MA, 02115, USA.
N L WaltonUniversity of Massachusetts Boston, Honors College of Nursing and Health Sciences, Boston, MA, 02125, USA.
K A MiczekTufts University School of Medicine, Department of Neuroscience, Boston, MA, 02111, USA.
J L MaguireTufts University School of Medicine, Department of Neuroscience, Boston, MA, 02111, USA. Jamie.Maguire@tufts.edu.ORCID http://orcid.org/0000-0002-4085-8605
Tufts University · USNortheastern University · USUniversity of Massachusetts Boston · US

Funding

TUSM/T-NEMC CENTER FOR NEUROSCIENCE RESEARCH - Imaging CoreP30NS047243 · NINDS · TUFTS UNIVERSITY BOSTON · PI JACKSON, F ROB · 2003 to 2017
$10.0M
Training in Education and Critical Research SkillsK12GM074869 · NIGMS · TUFTS UNIVERSITY BOSTON · PI MOORE, CLAIRE L · 2006 to 2017
$8.5M
Behavioral Neurobiology of Aggression: Alcohol, GABA, and 5-HTR01AA013983 · NIAAA · TUFTS UNIVERSITY MEDFORD · PI WEERA, MARCUS MATTHIAS · 2003 to 2022
$8.0M
Investigating the pathological consequences of seizure-induced activation of the HPA axisR01NS102937 · NINDS · TUFTS UNIVERSITY BOSTON · PI Jamie Lynn Maguire · 2017 to 2026
$4.2M
Building Diversity in Biomedical SciencesR25HL007785 · NHLBI · TUFTS UNIVERSITY BOSTON · PI MAGUIRE, JAMIE LYNN · 2008 to 2024
$2.0M
Interneurons tune the neural circuits mediating the anxiolytic effects of alcoholR01AA026256 · NIAAA · TUFTS UNIVERSITY BOSTON · PI MAGUIRE, JAMIE LYNN · 2018 to 2022
$1.9M
Investigating GABAergic control of the HPA axis in the co-morbidity of depressionR01NS073574 · NINDS · TUFTS UNIVERSITY BOSTON · PI MAGUIRE, JAMIE LYNN · 2011 to 2015
$1.7M
NIAAA NIH HHS R01 AA013983NIAAA NIH HHS R01 AA026256NIGMS NIH HHS K12 GM074869NINDS NIH HHS P30 NS047243NINDS NIH HHS R01 NS073574NINDS NIH HHS R01 NS102937NINDS NIH HHS R56 NS073574
6 · The paper itself

Abstract

Binge drinking is short-term drinking that achieves blood alcohol levels of 0.08 g/dl or above. It exhibits well-established sex differences in GABAergic inhibitory neurotransmission, including extrasynaptic δ subunit-containing GABA

Indexed as

Alcohol DrinkingAnimalsBinge DrinkingEthanolFemaleGene Knockdown TechniquesHumansMaleMiceReceptors, GABA-ASex CharacteristicsSynapsesSynaptic TransmissionVentral Tegmental AreaEthanolReceptors, GABA-A

Identifiers

PMID31147611
PMCPMC6542821
OpenAlexW2947987889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.