Evidence map›Paper›PMID 31147456›Full record

ArticleBioscience reports2019

Gut microbiota imbalances in Tunisian participants with type 1 and type 2 diabetes mellitus.

Meriem Fassatoui, Mireia Lopez-Siles, Diana A Díaz-Rizzolo, Haifa Jmel, Chokri Naouali, Ghaith Abdessalem, Asma Chikhaoui, Belén Nadal, Henda Jamoussi, Abdelmajid Abid and 4 more

Abstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. PeerJ · 2025
    Article
  14. Review
  15. Article
  16. The worldview ofFrontiers in microbiology · 2025
    Review
  17. Foods (Basel, Switzerland) · 2024
    Review
  18. Virulence · 2024
    Review
  19. Article
  20. Advances in fecal microbiota transplantation for the treatment of diabetes mellitus.Frontiers in cellular and infection microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Meriem FassatouiLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia.
Mireia Lopez-SilesLaboratory of Molecular Microbiology, Biology Department, Universitat de Girona, Maria Aurèlia Capmany, 40, 17003, Girona, Spain.
Diana A Díaz-RizzoloDiabetes and Obesity Research Laboratory, Institut d'Investigations Biomèdiques, August Pi I Sunyer (IDIBAPS), Hospital Clinic, Rosselló 149-153, 08036, Barcelona Spain.
Haifa JmelLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia.
Chokri NaoualiLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia.
Ghaith AbdessalemLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia.
Asma ChikhaouiLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia.
Belén NadalDiabetes and Obesity Research Laboratory, Institut d'Investigations Biomèdiques, August Pi I Sunyer (IDIBAPS), Hospital Clinic, Rosselló 149-153, 08036, Barcelona Spain.
Henda JamoussiLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia.
Abdelmajid AbidLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia.
Ramon GomisDiabetes and Obesity Research Laboratory, Institut d'Investigations Biomèdiques, August Pi I Sunyer (IDIBAPS), Hospital Clinic, Rosselló 149-153, 08036, Barcelona Spain.
Sonia AbdelhakLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia.
Margarita Martinez-MedinaLaboratory of Molecular Microbiology, Biology Department, Universitat de Girona, Maria Aurèlia Capmany, 40, 17003, Girona, Spain.
Rym KefiLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 13, Place Pasteur, B.P.74, 1002, Belvédère, Tunis, Tunisia rym.kefi@pasteur.rns.tn.ORCID 0000-0001-8801-5781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota plays an important role in the regulation of the immune system and host's metabolism. We aimed to characterize the gut microbiota of Tunisian participants with and without diabetes.We enrolled ten participants with type 1 diabetes mellitus (T1DM), ten patients with type 2 diabetes mellitus (T2DM), and 11 subjects without diabetes. Bacteria was quantified in fecal samples by quantitative PCR (qPCR). Statistical tests and multivariate analysis were performed using RStudio program.Results showed that the proportions of Firmicutes,

Indexed as

AdultAgedAkkermansiaBacillotaBacteroidetesBlood GlucoseDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Faecalibacterium prausnitziiFecesFemaleGastrointestinal MicrobiomeGastrointestinal TractGlycated HemoglobinHumansMaleBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanGut microbiotaqPCRTunisiantype 1 diabetes mellitustype 2 diabetes mellitus

Identifiers

PMID31147456
PMCPMC6579978

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.