Evidence map›Paper›PMID 31147388›Full record

ArticleGenes & development2019

PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability.

Ricardo J Cordeiro Rodrigues, António Miguel de Jesus Domingues, Svenja Hellmann, Sabrina Dietz, Bruno F M de Albuquerque, Christian Renz, Helle D Ulrich, Peter Sarkies, Falk Butter, René F Ketting

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  5. SLBP-independent control of maternal histone mRNA.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 5 countries.

Ricardo J Cordeiro RodriguesBiology of Non-coding RNA Group, Institute of Molecular Biology, 55128 Mainz, Germany.ORCID 0000-0002-0541-2229
António Miguel de Jesus DominguesBiology of Non-coding RNA Group, Institute of Molecular Biology, 55128 Mainz, Germany.ORCID 0000-0002-1803-1863
Svenja HellmannBiology of Non-coding RNA Group, Institute of Molecular Biology, 55128 Mainz, Germany.
Sabrina DietzInternational PhD Programme on Gene Regulation, Epigenetics, and Genome Stability, 55128 Mainz, Germany.
Bruno F M de AlbuquerqueBiology of Non-coding RNA Group, Institute of Molecular Biology, 55128 Mainz, Germany.
Christian RenzMaintenance of Genome Stability Group, Institute of Molecular Biology, 55128 Mainz, Germany.ORCID 0000-0003-3164-3597
Helle D UlrichMaintenance of Genome Stability Group, Institute of Molecular Biology, 55128 Mainz, Germany.ORCID 0000-0003-0431-2223
Peter SarkiesMedical Research Council London Institute of Medical Sciences, London W12 0NN, United Kingdom.ORCID 0000-0003-0279-6199
Falk ButterQuantitative Proteomics Group, Institute of Molecular Biology, 55128 Mainz, Germany.
René F KettingBiology of Non-coding RNA Group, Institute of Molecular Biology, 55128 Mainz, Germany.ORCID 0000-0001-6161-5621
Institute of Molecular Biology · DEGene Therapy Laboratory · FRImperial College London · GBQuantitative BioSciences · USUniversidade do Porto · PT

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Medical Research Council MC_UP_1102/13NIH HHS P40 OD010440
6 · The paper itself

Abstract

Piwi proteins are important for germ cell development in most animals. These proteins are guided to specific targets by small guide RNAs, referred to as piRNAs or 21U RNAs in

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsEmbryo, NonmammalianMultiprotein ComplexesRNA, Small NuclearRNA, Small NucleolarCaenorhabditis elegans ProteinsMultiprotein ComplexesRNA, Small NuclearRNA, Small Nucleolar21U RNAC. elegansenhancer of rudimentaryIFE-3MID domainPID-1PID-3piRNAPRG-1TOFU-6

Identifiers

PMID31147388
PMCPMC6601512
OpenAlexW2953205579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.