Evidence map›Paper›PMID 31147384›Full record

ArticleThe Journal of cell biology2019

Scribble, Erbin, and Lano redundantly regulate epithelial polarity and apical adhesion complex.

Jongho Choi, Regina B Troyanovsky, Indrajyoti Indra, Brian J Mitchell, Sergey M Troyanovsky

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
10.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Neuron-Specific Deletion ofFrontiers in genetics · 2022
    Article
  15. Article
  16. Article
  17. Transcriptional Control of Apical-Basal Polarity Regulators.International journal of molecular sciences · 2021
    Review
  18. Review
  19. Evidence for a nuclear role forMolecular biology of the cell · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jongho Choi *Department of Dermatology, Northwestern University, The Feinberg School of Medicine, Chicago, IL.ORCID 0000-0003-3091-2118
Regina B Troyanovsky *Department of Dermatology, Northwestern University, The Feinberg School of Medicine, Chicago, IL.
Indrajyoti IndraDepartment of Dermatology, Northwestern University, The Feinberg School of Medicine, Chicago, IL.ORCID 0000-0001-5381-7397
Brian J MitchellDepartment of Cell and Molecular Biology, The Feinberg School of Medicine, Chicago, IL.ORCID 0000-0001-6281-1536
Sergey M TroyanovskyDepartment of Dermatology, Northwestern University, The Feinberg School of Medicine, Chicago, IL s-troyanovsky@northwestern.edu.ORCID 0000-0001-7368-9708
Northwestern University · USUniversity of Chicago · US

Funding

Inter-junctional signaling in epithelial junctional complexR01AR044016 · NIAMS · WASHINGTON UNIVERSITY · PI TROYANOVSKY, SERGEY M · 1996 to 2020
$6.8M
Molecular Regulation of Radial IntercalationR01GM113922 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MITCHELL, BRIAN JOSEPH · 2017 to 2025
$2.7M
Functional and Structural Links between Cadherin, Gamma-Secretase, and NotchR01AR057992 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TROYANOVSKY, SERGEY M · 2010 to 2014
$1.6M
Inter-junctional signaling in epithelial junctional complexR56AR044016 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TROYANOVSKY, SERGEY M · 2015 to 2015
$435k
NIAMS NIH HHS R01 AR044016NIAMS NIH HHS R01 AR057992NIAMS NIH HHS R56 AR044016NIGMS NIH HHS R01 GM113922
6 · The paper itself

Abstract

The basolateral protein Scribble (Scrib), a member of the LAP protein family, is essential for epithelial apicobasal polarity (ABP) in

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCarrier ProteinsCell AdhesionCell MembraneCell PolarityDrosophila melanogasterDrosophila ProteinsEpithelial CellsGene EditingHumansIntercellular JunctionsMembrane ProteinsStructure-Activity RelationshipAdaptor Proteins, Signal TransducingCarrier ProteinsDrosophila ProteinsERBIN protein, humanLRRC1 protein, humanMembrane ProteinsScrib protein, Drosophila

Identifiers

PMID31147384
PMCPMC6605793
OpenAlexW2948009614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.