Evidence map›Paper›PMID 31147353›Full record

ArticleAJNR. American journal of neuroradiology2019

Deep Learning-Based Automatic Segmentation of Lumbosacral Nerves on CT for Spinal Intervention: A Translational Study.

G Fan, H Liu, Z Wu, Y Li, C Feng, D Wang, J Luo, W M Wells, S He

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. 3D U-net for volumetric segmentation of spinal cord MRI in degenerative disorders.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Review
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  10. Artificial intelligence in spine care: current applications and future utility.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Review
  11. Review
  12. Machine Learning Algorithms in Neuroimaging: An Overview.Acta neurochirurgica. Supplement · 2022
    Review
  13. A novel dual-network architecture for mixed-supervised medical image segmentation.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2021
    Article
  14. Article
  15. Mixed-Supervised Dual-Network for Medical Image Segmentation.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

G FanFrom the Orthopedic Department, Shanghai Tenth People's Hospital (G.F., C.F., D.W., S.H.), Tongji University School of Medicine, Shanghai, China tjhss7418@tongji.edu.cn gfan@tongji.edu.cn.ORCID 0000-0002-6418-8343
H LiuSpinal Pain Research Institute of Tongji University (H.L., C.F., D.W., S.H.), Shanghai, China.ORCID 0000-0001-7492-9275
Z WuSchool of Data and Computer Science (Z.W.), Sun Yat-sen University, Guangzhou, China.ORCID 0000-0003-4878-9509
Y LiShanghai Jiao Tong University School of Medicine (Y.L.), Shanghai, China.ORCID 0000-0001-7365-7490
C FengFrom the Orthopedic Department, Shanghai Tenth People's Hospital (G.F., C.F., D.W., S.H.), Tongji University School of Medicine, Shanghai, China.ORCID 0000-0002-2737-573X
D WangFrom the Orthopedic Department, Shanghai Tenth People's Hospital (G.F., C.F., D.W., S.H.), Tongji University School of Medicine, Shanghai, China.ORCID 0000-0001-5143-3947
J LuoSurgical Planning Lab (G.F., J.L., W.M.W.), Radiology Department, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-1437-2214
W M WellsSurgical Planning Lab (G.F., J.L., W.M.W.), Radiology Department, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-4279-8634
S HeFrom the Orthopedic Department, Shanghai Tenth People's Hospital (G.F., C.F., D.W., S.H.), Tongji University School of Medicine, Shanghai, China tjhss7418@tongji.edu.cn gfan@tongji.edu.cn.ORCID 0000-0001-7796-1510

Funding

Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
NIBIB NIH HHS P41 EB015898
6 · The paper itself

Abstract

background and purpose3D reconstruction of a targeted area ("safe" triangle and Kambin triangle) may benefit the viability assessment of transforaminal epidural steroid injection, especially at the L5/S1 level. However, manual segmentation of lumbosacral nerves for 3D reconstruction is time-consuming. The aim of this study was to investigate the feasibility of deep learning-based segmentation of lumbosacral nerves on CT and the reconstruction of the safe triangle and Kambin triangle. MATERIALS AND

methodsA total of 50 cases of spinal CT were manually labeled for lumbosacral nerves and bones using Slicer 4.8. The ratio of training/validation/testing was 32:8:10. A 3D U-Net was adopted to build the model SPINECT for automatic segmentations of lumbosacral structures. The Dice score, pixel accuracy, and Intersection over Union were computed to assess the segmentation performance of SPINECT. The areas of Kambin and safe triangles were measured to validate the 3D reconstruction.

resultsThe results revealed successful segmentation of lumbosacral bone and nerve on CT. The average pixel accuracy for bone was 0.940, and for nerve, 0.918. The average Intersection over Union for bone was 0.897 and for nerve, 0.827. The Dice score for bone was 0.945, and for nerve, it was 0.905. There were no significant differences in the quantified Kambin triangle or safe triangle between manually segmented images and automatically segmented images (

conclusionsDeep learning-based automatic segmentation of lumbosacral structures (nerves and bone) on routine CT is feasible, and SPINECT-based 3D reconstruction of safe and Kambin triangles is also validated.

Indexed as

Deep LearningHumansImaging, Three-DimensionalLumbosacral PlexusLumbosacral RegionNeuroimagingRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID31147353
PMCPMC6746413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.