ArticleBMC cancer2019
Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patients.
Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Psychometric Performance of Generic Preference-Based Measures in Informal Carers: A Systematic Review of Validation Studies.PharmacoEconomics · 2025Pooled it
- Measurement Properties of Commonly Used Generic Preference-Based Measures in East and South-East Asia: A Systematic Review.PharmacoEconomics · 2020Pooled it
- Cost-Effectiveness of the Comprehensive Interdisciplinary Program-Care in Informal Caregivers of People with Alzheimer's Disease.International journal of environmental research and public health · 2022Trial
- Association Between Health-Related Quality of Life In Patients with Colorectal Cancer and Their Informal Caregivers.Advances in therapy · 2026Article
- Anxiety and depression may amplify self-reported physical health problems: evidence from EQ-5D-5L data.Health and quality of life outcomes · 2026Article
- Association between team functioning and self-efficacy and quality of life for primary care patients in British Columbia, Nova Scotia, and Ontario.Primary health care research & development · 2026Article
- Perceived economic pressure and health-related quality of life of patients with colorectal cancer after surgery: Evidence from China.Journal of family medicine and primary care · 2025Article
- Digital Health Literacy and Physical Activity Programme for Improvement of Quality of Life in Caregivers of People with Dementia (CAREFIT): Study Protocol.Healthcare (Basel, Switzerland) · 2025Article
- Assessing the psychometric performance of the EQ-5D-5L among informal caregivers of people with dementia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Long-term outcomes in sacral agenesis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- A head-to-head comparison of the measurement properties of EQ-5D-3L and EQ-5D-5L in Chinese family caregivers of cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Article
- Comparing EQ-5D-3L and EQ-5D-5L in measuring the HRQoL burden of 4 health conditions in China.The European journal of health economics : HEPAC : health economics in prevention and care · 2023Article
- Health-related quality of life of patients with haemophilia: a cross-sectional survey in the Northeast of China.BMJ open · 2022Article
- Psychometric properties of the EQ-5D-5L compared with EQ-5D-3L in cancer patients in Iran.Frontiers in oncology · 2022Article
- Comparing the measurement properties of the EQ-5D-5L and the EQ-5D-3L in hypertensive patients living in rural China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- A head-to-head comparison of measurement properties of the EQ-5D-3L and EQ-5D-5L in acute myeloid leukemia patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Health-Related Quality of Life and Its Influencing Factors for Elderly Patients With Hypertension: Evidence From Heilongjiang Province, China.Frontiers in public health · 2021Article
- Is retrospective assessment of health-related quality of life valid?BMC musculoskeletal disorders · 2020Article
- Investigating psychometric properties of the Thai version of the Zarit Burden Interview using rasch model and confirmatory factor analysis.BMC research notes · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
purposeThis study aimed to test the validity and reliability of the five-level EuroQol five-dimensional (EQ-5D-5 L) instrument in family caregivers (FCs) of leukemia patients in Heilongjiang of China.
methodsA cross-sectional survey was conducted on 298 family caregivers (FCs) of leukemia patients from three major cancer centers in the capital city of Heilongjiang province of China. Their dimensional scores of the EQ-5D-5 L were compared with those of the WHOQOL-BREF to test the convergent validity (constructs measuring the same concept) and divergent validity (constructs measuring different concepts) of the EQ-5D-5 L. Repeated surveys were conducted on 271 participants to determine the test-retest reliability of the EQ-5D-5 L.
resultsThe four physical dimensions (mobility, self-care, usual activities, and pain/discomfort) of the EQ-5D-5 L had moderate or high correlations with the physical health domain of the WHOQOL-BREF, with a correlation coefficient (r) ranging from 0.459 to 0.559. The anxiety/depression dimension of the EQ-5D-5 L had a high correlation (r = 0.667) with the psychological domain of the WHOQOL-BREF. By contrast, lower but still significant physical-to-psychological correlations were found between the two instruments (r ranging from 0.219 to 0.396). In addition, the EQ-5D-5 L dimensional scores showed no or weak correlations with the environment and social domains of the WHOQOL-BREF (r ranging from 0.016 to 0.207). High test-retest reliability (> 0.7) was evident.
conclusionThe Chinese version of the EQ-5D-5 L has satisfactory reliability and validity in FCs of leukemia patients. It can be used to elicit utility of health-related quality of life in FCs of leukemia.
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