Observational studyBMC nephrology2019
Association of gait speed and grip strength with risk of cardiovascular events in patients on haemodialysis: a prospective study.
Observational study in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06624358 (Physical Activity in Adolescents With Chronic Kidney Disease), which is not on this map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physical Activity in Adolescents With Chronic Kidney Disease
Who cites it
14 citing papers in PubMed.
- The prognostic value of gait speed in hemodialysis patients: A prospective observational study.PloS one · 2026Observational
- Bioelectrical impedance analysis and physical function improved risk prediction for cardiac dysfunction in hemodialysis patients.Frontiers in physiology · 2026Article
- The association between hand grip strength and chronic kidney disease progression: insights from SMP-CKD studies.International urology and nephrology · 2025Observational
- Association of combined left and right handgrip strength with new-onset chronic kidney disease in middle-aged and older adults: a nationwide multicenter cohort study.BMC public health · 2025Observational
- Assessment of Frailty Among Older Adults in the Physical Activity Daily Trial.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024Observational
- Association between gait video information and general cardiovascular diseases: a prospective cross-sectional study.European heart journal. Digital health · 2024Article
- Handgrip strength is associated with cognitive function in older patients with stage 3-5 chronic kidney disease: results from the NHANES.Scientific reports · 2024Article
- Plasma metabolites and physical function in patients undergoing hemodialysis.Scientific reports · 2024Article
- Association of handgrip strength and/or walking pace with incident chronic kidney disease: A UK biobank observational study.Journal of cachexia, sarcopenia and muscle · 2023Observational
- Dynapenia is an independent predictor of cardio-cerebrovascular events in patients undergoing hemodialysis.Heart and vessels · 2022Article
- Mortality of Japanese Olympic athletes in 1964 Tokyo Olympic Games.BMJ open sport & exercise medicine · 2021Article
- The cut-off values of handgrip strength and lean mass index for sarcopenia among patients on peritoneal dialysis.Nutrition & metabolism · 2020Article
- Mobility Impairment in Patients New to Dialysis.American journal of nephrology · 2020Observational
- Analysis of sarcopenia parameters and falls in hemodialysis patients: no association found in a cross-sectional study.Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGait speed (GS) and handgrip strength (HGS), both factors associated with frailty and sarcopenia, are reportedly associated with CV events in the general population. However, little is known about the impact of these factors on the outcome of patients on dialysis. This study aimed to evaluate whether evaluation of GS and HGS could be associated the onset of fatal/non-fatal cardiovascular (CV) events in patients on haemodialysis (HD).
methodsOne-hundred-eighty-two patients with end-stage renal disease (ESRD) undergoing HD at four dialysis clinics in April 2015 provided written informed consent to participate in the study. We excluded patients who had physical disability, were unable to walk without help, or had recently experienced CV events. Usual GS over a 4-m walk and HGS were measured at baseline, and 173 patients (men, 124; women, 49) were divided into sex-specific quartiles according to GS and HGS and were followed-up for fatal/non-fatal CV events for a median of 2 years. We examined the association of GS and HGS with CV events and determined cut-off values using Cox regression analysis adjusted for age, sex, HD duration, history of CVD, and diabetes.
resultsDuring the follow-up period, 46 CV events occurred. Both physical performance factors were significantly associated with CV events. Low GS (< 0.82 m/s for men and 0.81 m/s for women) and weak HGS (< 29.0 kg for men and 19.7 kg for women) were associated with CV events. For low vs. high GS, the hazard ratio (HR) for CV events was 2.29 [95% confidence interval (CI): 1.20-4.33; P = 0.01], and for low vs. high HGS, the HR was 2.15 [95% CI: 1.00-5.04; P < 0.05]. These HRs remained significant after adjusting for confounding factors, such as sex, age, dialysis vintage, history of CV disease, and diabetes.
conclusionsSlow GS and weak HGS in patients on HD were suggested to be independent predictors of fatal/non-fatal CV events.
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