Evidence map›Paper›PMID 31146673›Full record

SynthesisThe journal of headache and pain2019

Clinical features of visual migraine aura: a systematic review.

Michele Viana, Erling Andreas Tronvik, Thien Phu Do, Chiara Zecca, Anders Hougaard

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in The journal of headache and pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Spreading depolarization: A wave that precedes and drives cerebral ischemic cell death-Target for neuroprotection.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
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  9. Neuro-ophthalmology and migraine: visual aura and its neural basis.International journal of emergency medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Michele VianaHeadache Center, Neurocenter of Southern Switzerland (NSI), Regional Hospital Lugano, Via Tesserete 46, 6901, Lugano, Switzerland. michele.viana@ymail.com.ORCID http://orcid.org/0000-0003-4356-8109
Erling Andreas TronvikDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.
Thien Phu DoDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Glostrup, Denmark.
Chiara ZeccaHeadache Center, Neurocenter of Southern Switzerland (NSI), Regional Hospital Lugano, Via Tesserete 46, 6901, Lugano, Switzerland.
Anders HougaardDanish Headache Center, Department of Neurology, Rigshospitalet Glostrup, Glostrup, Denmark.
Glostrup Hospital · DKKing's College London · GBNorwegian University of Science and Technology · NOOspedale regionale di Lugano · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMigraine aura (MA) is a common and disabling neurological condition, characterized by transient visual, and less frequently sensory and dysphasic aura disturbances. MA is associated with an increased risk of cardiovascular disorders and is often clinically difficult to distinguish from other serious neurological disorders such as transient ischemic attacks and epilepsy. Optimal clinical classification of MA symptoms is important for more accurate diagnosis and improved understanding of the pathophysiology of MA through clinical studies. MAIN BODY: A systematic review of previous prospective and retrospective systematic recordings of visual aura symptoms (VASs) was performed to provide an overview of the different types of visual phenomena occurring during MA and their respective frequencies in patients. We found 11 retrospective studies and three prospective studies systematically describing VASs. The number of different types of VASs reported by patients in the studies ranged from two to 23. The most common were flashes of bright light, "foggy" vision, zigzag lines, scotoma, small bright dots and 'like looking through heat waves or water'.

conclusionsWe created a comprehensive list of VAS types reported by migraine patients based on all currently available data from clinical studies, which can be used for testing and validation in future studies. We propose that, based on this work, an official list of VAS types should be developed, preferably within the context of the International Classification of Headache Disorders of the International Headache Society.

Indexed as

AdultEpilepsyFemaleHallucinationsHumansIschemic Attack, TransientMaleMigraine with AuraProspective StudiesRetrospective StudiesVision, OcularBlurred visionClinical featuresMigraine auraMigraine with auraScintillating scotomaScotomaVisual disturbancesVisual symptomsZigzag lines

Identifiers

PMID31146673
PMCPMC6734223
OpenAlexW2947550920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.