Evidence map›Paper›PMID 31146509›Full record

ReviewIntestinal research2019

Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia.

Choon Jin Ooi, Ida Hilmi, Rupa Banerjee, Sai Wei Chuah, Siew Chien Ng, Shu Chen Wei, Govind K Makharia, Pises Pisespongsa, Min Hu Chen, Zhi Hua Ran and 24 more

Open access · diamondAbstract readReview
In one paragraph

Review in Intestinal research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.

  1. Guideline
  2. Trial
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  7. Review
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  9. Article
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  12. Collagen Peptides andFood science & nutrition · 2025
    Article
  13. Review
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  18. Risk Factors ofGut and liver · 2024
    Article
  19. Review
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 20 institutions in 14 countries.

Choon Jin OoiDepartment of Gastroenterology and Hepatology, Singapore General Hospital, Singapore.
Ida Hilmi
Rupa BanerjeeAsian Institute of Gastroenterology, New Delhi, India.
Sai Wei ChuahGleneagles Medical Centre, Singapore.
Siew Chien NgDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Shu Chen WeiDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Govind K MakhariaDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
Pises PisespongsaGastroenterology and Hepatology, Bumrungrad International University, Bangkok, Thailand.
Min Hu ChenDivision of Gastroenterology, The First University Hospital, Sun Yat-sen University, Guangzhou, China.
Zhi Hua RanDepartment of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Byong Duk YeDepartment of Gastroenterology and IBD Center, University of Ulsan College of Medicine, Seoul, Korea.
Dong Il ParkDepartment of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Khoon Lin LingDuke-NUS Medical School, Singapore.
David OngDivision of Gastroenterology and Hepatology, National University Hospital of Singapore, University Medicine Cluster, Singapore.
Vineet AhujaDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Khean Lee GohUniversity of Malaya Specialist Centre, Kuala Lumpur, Malaysia.
Jose SollanoDepartment of Medicine, University of Santo Tomas, Manila, Philippines.
Wee Chian LimDepartment of Gastroenterology and Hepatology, Tan Tock Seng Hospital, Singapore.
Wai Keung LeungDivision of Gastroenterology and Hepatology, Department of Medicine, University of Hong Kong, Hong Kong.
Raja Affendi Raja AliFaculty of Medicine, UKM Medical and Specialist Centres, The National University of Malaysia, Kuala Lumpur, Malaysia.
Deng Chyang WuDepartment of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Evan OngDepartment of Medicine, University of Santo Tomas, Manila, Philippines.
Nazri MustaffaDepartment of Internal Medicine, School of Medical Sciences, Health Campus, Sains University, Kubang Kerian, Malaysia.
Julajak LimsrivilaiDepartment of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Tadakazu HisamatsuThe Third Department of Internal Medicine, Kyorin University School of Medicine, Mitaka, Japan.
Suk Kyun YangDepartment of Gastroenterology, University of Ulsan College of Medicine, Seoul, Korea.
Qin OuyangDepartment of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China.
Richard GearyDepartment of Medicine, University of Otago, Christchurch, New Zealand.
Janaka H De SilvaFaculty of Medicine, University of Kelaniya, Dalugama, Sri Lanka.
Rungsun RerknimitrDepartment of Medicine, Chulalongkorn University, Bangkok, Thailand.
Marcellus SimadibrataDepartment of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
Murdani AbdullahDivision of Gastroenterology, Department of Internal Medicine, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia.
Rupert Wl LeongGastroenterology and Liver Services, Concord Hospital, Sydney, Australia.
Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease and Asian Organization for Crohn’s and ColitisDepartment of Gastroenterology and Hepatology, Singapore General Hospital, Singapore.
National Taiwan University Hospital · TWUlsan College · KRUniversity Malaya Medical Centre · MYUniversity of Santo Tomas · PHAll India Institute of Medical Sciences · INAsian Institute of Gastroenterology · INBumrungrad International Hospital · THChinese University of Hong Kong · HKChulalongkorn University · THConcord Repatriation General Hospital · AUDuke-NUS Medical School · SGGleneagles Hospital · SGKangbuk Samsung Hospital · KRKaohsiung Medical University · TWKyorin University · JPNational University Hospital · SGNational University of Malaysia · MYRumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo · IDShanghai Jiao Tong University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Asia-Pacific Working Group on inflammatory bowel disease (IBD) was established in Cebu, Philippines, under the auspices of the Asian Pacific Association of Gastroenterology with the goal of improving IBD care in Asia. This consensus is carried out in collaboration with Asian Organization for Crohn's and Colitis. With biologic agents and biosimilars becoming more established, it is necessary to conduct a review on existing literature and establish a consensus on when and how to introduce biologic agents and biosimilars in the conjunction with conventional treatments for ulcerative colitis (UC) and Crohn's disease (CD) in Asia. These statements also address how pharmacogenetics influence the treatments of UC and CD and provide guidance on response monitoring and strategies to restore loss of response. Finally, the review includes statements on how to manage treatment alongside possible hepatitis B and tuberculosis infections, both common in Asia. These statements have been prepared and voted upon by members of IBD workgroup employing the modified Delphi process. These statements do not intend to be all-encompassing and future revisions are likely as new data continue to emerge.

Indexed as

AdalimumabColitis, ulcerativeCrohn diseaseInflammatory bowel diseaseInfliximab

Identifiers

PMID31146509
PMCPMC6667368
OpenAlexW2940861103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.