Evidence map›Paper›PMID 31146462›Full record

ReviewNutrients2019

Microalgal Derivatives as Potential Nutraceutical and Food Supplements for Human Health: A Focus on Cancer Prevention and Interception.

Christian Galasso, Antonio Gentile, Ida Orefice, Adrianna Ianora, Antonino Bruno, Douglas M Noonan, Clementina Sansone, Adriana Albini, Christophe Brunet

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 288 citations in OpenAlex.

  1. Review
  2. Article
  3. Nutraceutical and Antitumoral Potential ofFoods (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Convective Drying of Brown Seaweed (Foods (Basel, Switzerland) · 2025
    Article
  6. Foods (Basel, Switzerland) · 2025
    Article
  7. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Effectiveness effects ofOpen veterinary journal · 2025
    Article
  16. Review
  17. Advances in Bioprocess Engineering for OptimisingFoods (Basel, Switzerland) · 2024
    Review
  18. Article
  19. Review
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Christian GalassoStazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy. christian.galasso@szn.it.ORCID 0000-0002-1262-959X
Antonio GentileStazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy. antonio.gentile@szn.it.
Ida OreficeStazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy. ida.orefice@szn.it.
Adrianna IanoraStazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy. adrianna.ianora@szn.it.
Antonino BrunoLaboratory of Vascular Biology and Angiogenesis, IRCCS MultiMedica, 20138 Milan, Italy. 82antonino.bruno@gmail.com.ORCID 0000-0002-4790-0861
Douglas M NoonanLaboratory of Vascular Biology and Angiogenesis, IRCCS MultiMedica, 20138 Milan, Italy. douglas.noonan@uninsubria.it.
Clementina SansoneStazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy. clementina.sansone@szn.it.
Adriana AlbiniLaboratory of Vascular Biology and Angiogenesis, IRCCS MultiMedica, 20138 Milan, Italy. adriana.albini@unimib.it.
Christophe BrunetStazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy. christophe.brunet@szn.it.
Stazione Zoologica Anton Dohrn · ITMultiMedica · ITUniversity of Insubria · IT

Funding

Regione Campania PG/2018/0494374
6 · The paper itself

Abstract

Epidemiological studies are providing strong evidence on beneficial health effects from dietary measures, leading scientists to actively investigate which foods and which specific agents in the diet can prevent diseases. Public health officers and medical experts should collaborate toward the design of disease prevention diets for nutritional intervention. Functional foods are emerging as an instrument for dietary intervention in disease prevention. Functional food products are technologically developed ingredients with specific health benefits. Among promising sources of functional foods and chemopreventive diets of interest, microalgae are gaining worldwide attention, based on their richness in high-value products, including carotenoids, proteins, vitamins, essential amino acids, omega-rich oils and, in general, anti-inflammatory and antioxidant compounds. Beneficial effects of microalgae on human health and/or wellness could in the future be useful in preventing or delaying the onset of cancer and cardiovascular diseases. During the past decades, microalgal biomass was predominately used in the health food market, with more than 75% of the annual microalgal biomass production being employed for the manufacture of powders, tablets, capsules or pastilles. In this review, we report and discuss the present and future role of microalgae as marine sources of functional foods/beverages for human wellbeing, focusing on perspectives in chemoprevention. We dissected this topic by analyzing the different classes of microalgal compounds with health outputs (based on their potential chemoprevention activities), the biodiversity of microalgal species and how to improve their cultivation, exploring the perspective of sustainable food from the sea.

Indexed as

Dietary SupplementsFunctional FoodAnimalsAnticarcinogenic AgentsAntineoplastic AgentsCell Transformation, NeoplasticDiet, HealthyHumansMicroalgaeNeoplasmsNutritive ValueProtective FactorsRisk FactorsAnticarcinogenic AgentsAntineoplastic Agentscancerchemopreventionfunctional foodmarine bioactive compoundsmicroalgaenutraceutical

Identifiers

PMID31146462
PMCPMC6627306
OpenAlexW2947734847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.