Evidence map›Paper›PMID 31146377›Full record

ArticleMarine drugs2019

Potential TSPO Ligand and Photooxidation Quencher Isorenieratene from Arctic Ocean

Yashu Chen, Mengyao Guo, Jifang Yang, Jigang Chen, Bijun Xie, Zhida Sun

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. International journal of systematic and evolutionary microbiology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. The Inhibition of Antibiotic Production inFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yashu ChenNatural Product Laboratory, Department of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. yashuchen@sina.com.
Mengyao GuoAgricultural Bioinformatics Key Laboratory of Hubei Province, College of informatics, Huazhong Agricultural University, Wuhan 430070, China. guomengyao96@gmail.com.
Jifang YangCollege of Biological and Environmental Science, Zhejiang Wanli University, Ningbo 315100, China. jfkwlq@163.com.
Jigang ChenCollege of Biological and Environmental Science, Zhejiang Wanli University, Ningbo 315100, China. genomic@163.com.
Bijun XieNatural Product Laboratory, Department of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. bijunxie@sina.com.
Zhida SunNatural Product Laboratory, Department of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. sunzhida@mail.hzau.edu.cn.ORCID 0000-0003-2822-4367
Huazhong Agricultural University · CNZhejiang Wanli University · CN

Funding

The China national Marine Scientific Public Welfare 201405015-5the Key Science and Technology Program of Ningbo City, Zhejiang Province, China 2012C10038
6 · The paper itself

Abstract

Due to its special aromatic structure, isorenieratene is thought to be an active natural antioxidant and photo/UV damage inhibitor. In this work, isorenieratene that was extracted from Rhodococcus sp. B7740 isolated from the Arctic Ocean, showed excellent scavenging ability of both singlet oxygen and hydroxyl radical in the UVB-induced auto-oxidation process using the EPR method. Within an ARPE-19 cell model damaged by UVB radiation, isorenieratene showed fine protective effects (1.13 ± 0.03 fold) compared with macular xanthophylls (MXs) through upregulating of

Indexed as

AnimalsArctic RegionsCarotenoidsCell LineCellsCytoprotectionHumansLigandsMiceModels, MolecularOceans and SeasOxidative StressPhenolsPlant ExtractsProtein Structure, TertiaryRadiation-Protective AgentsCarotenoidsisorenierateneLigandsPhenolsPlant ExtractsRadiation-Protective AgentsReceptors, GABATSPO protein, humanantioxidant and anti-UVB radiationEPRisorenieratenemacular xanthophyllsTSPO

Identifiers

PMID31146377
PMCPMC6627809
OpenAlexW2947806372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.