Evidence map›Paper›PMID 31146371›Full record

ArticleViruses2019

Recombinant Strains of Human Parechovirus in Rural Areas in the North of Brazil.

Élcio Leal, Adriana Luchs, Flávio Augusto de Pádua Milagres, Shirley Vasconcelos Komninakis, Danielle Elise Gill, Márcia Cristina Alves Brito Sayão Lobato, Rafael Brustulin, Rogério Togisaki das Chagas, Maria de Fátima Neves Dos Santos Abrão, Cássia Vitória de Deus Alves Soares and 6 more

Abstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Journal of virology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Élcio LealInstituto de Ciências Biológicais, Universidade Federal do Pará, Pará 66075-000, Brazil. elcioleal@gmail.com.ORCID 0000-0003-3463-0492
Adriana LuchsLaboratório de Doenças Entéricas, Centro de Virologia, Instituto Adolfo Lutz, São Paulo 01246-000, Brazil. driluchs@gmail.com.
Flávio Augusto de Pádua MilagresLIM/46, Faculdade de Medicina, Universidade de São Paulo, São Paulo 01246-903, Brazil. flaviomilagres@uft.edu.br.
Shirley Vasconcelos KomninakisFaculdade de Medicina do ABC, Santo André 09060-870, Brazil. skomninakis@yahoo.com.br.
Danielle Elise GillInstituto de Medicina Tropical, Universidade de São Paulo, São Paulo 05403-000, Brazil. degill@g.clemson.edu.
Márcia Cristina Alves Brito Sayão LobatoSecretaria de Saúde do Tocantins, Tocantins 77453-000, Brazil. eumarciaalvesbrito@gmail.com.
Rafael BrustulinSecretaria de Saúde do Tocantins, Tocantins 77453-000, Brazil. eu3rafael@gmail.com.
Rogério Togisaki das ChagasSecretaria de Saúde do Tocantins, Tocantins 77453-000, Brazil. chagastogisaki@hotmail.com.
Maria de Fátima Neves Dos Santos AbrãoSecretaria de Saúde do Tocantins, Tocantins 77453-000, Brazil. fatima_abrao@yahoo.com.br.
Cássia Vitória de Deus Alves SoaresSecretaria de Saúde do Tocantins, Tocantins 77453-000, Brazil. cassiavitoriaalves@gmail.com.
Fabiola VillanovaInstituto de Ciências Biológicais, Universidade Federal do Pará, Pará 66075-000, Brazil. fevface@gmail.com.
Steven S WitkinInstituto de Medicina Tropical, Universidade de São Paulo, São Paulo 05403-000, Brazil. switkin@med.cornell.edu.
Xutao DengBlood Systems Research Institute, San Francisco, CA 94143, USA. xdeng@bloodsystems.org.
Ester Cerdeira SabinoLIM/46, Faculdade de Medicina, Universidade de São Paulo, São Paulo 01246-903, Brazil. sabinoec@gmail.com.ORCID 0000-0003-2623-5126
Eric DelwartBlood Systems Research Institute, San Francisco, CA 94143, USA. eric.delwart@ucsf.edu.
Antônio Charlys da CostaInstituto de Medicina Tropical, Universidade de São Paulo, São Paulo 05403-000, Brazil. charlysbr@yahoo.com.br.ORCID 0000-0001-5516-5177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We characterized the 24 nearly full-length genomes of human parechoviruses (PeV) from children in the north of Brazil. The initial phylogenetic analysis indicated that 17 strains belonged to genotype 1, 5 to genotype 4, and 1 to genotype 17. A more detailed analysis revealed a high frequency of recombinant strains (58%): A total of 14 of our PeV-As were chimeric, with four distinct recombination patterns identified. Five strains were composed of genotypes 1 and 5 (Rec1/5); five strains shared a complex mosaic pattern formed by genotypes 4, 5, and 17 (Rec4/17/5); two strains were composed of genotypes 1 and 17 (Rec1/17); and two strains were composed of genotype 1 and an undetermined strain (Rec1/und). Coalescent analysis based on the

Indexed as

Genome, ViralRecombination, GeneticBrazilChild, PreschoolFecesGastroenteritisGenetic VariationGenotypeHumansInfantMiddle AgedParechovirusPhylogenyPicornaviridae InfectionsReassortant VirusesRNA, ViralRNA, ViralViral ProteinsBrazilcoalescentparechoviruspicornavirusrecombinationvirome

Identifiers

PMID31146371
PMCPMC6630568

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.