Evidence map›Paper›PMID 31146203›Full record

ArticleDrug and alcohol dependence2019

A comparison of the utility of urine- and hair testing in detecting self-reported drug use among young adult opioid users.

Joseph J Palamar, Austin Le, Honoria Guarino, Pedro Mateu-Gelabert

Open access · greenAbstract readComparative Study
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Joseph J PalamarDepartment of Population Health, NYU School of Medicine, New York, NY, USA; Center for Drug Use and HIV/HCV Research, NYU College of Global Public Health, 665 Broadway, New York, NY, USA. Electronic address: joseph.palamar@nyulangone.org.
Austin LeDepartment of Population Health, NYU School of Medicine, New York, NY, USA; New York University College of Dentistry, 345 E. 24th Street, 1st Avenue, New York, NY, USA.
Honoria GuarinoCenter for Drug Use and HIV/HCV Research, NYU College of Global Public Health, 665 Broadway, New York, NY, USA; National Development and Research Institutes, 71 W 23rd St, New York, NY, USA.
Pedro Mateu-GelabertCenter for Drug Use and HIV/HCV Research, NYU College of Global Public Health, 665 Broadway, New York, NY, USA; National Development and Research Institutes, 71 W 23rd St, New York, NY, USA.
National Development and Research Institutes · USNew York City Health and Hospitals Corporation · USNew York University · US

Funding

The Staying Safe Intervention: Preventing HCV among Young Opioid InjectorsR01DA041501 · NIDA · NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. · PI GUARINO, HONORIA M, MATEU-GELABERT, PEDRO · 2016 to 2020
$3.6M
HIV, HCV and STI Risk Associated with Nonmedical Use of Prescription OpioidsR01DA035146 · NIDA · NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. · PI MATEU-GELABERT, PEDRO · 2013 to 2017
$2.9M
Accessible Care Intervention for Engaging People who Inject Illicit Drugs (PWID) in Hepatitis C CareR01DA041298 · NIDA · NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. · PI MARKS, KRISTEN M, MATEU-GELABERT, PEDRO · 2016 to 2020
$2.8M
Drug use among nightclub and dance festival attendees in New York CityR01DA044207 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PALAMAR, JOSEPH J · 2018 to 2021
$1.5M
Development of a Rapid Survey to Detect Use of New and Emerging DrugsK01DA038800 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PALAMAR, JOSEPH J · 2015 to 2019
$879k
NIDA NIH HHS K01 DA038800NIDA NIH HHS R01 DA035146NIDA NIH HHS R01 DA041298NIDA NIH HHS R01 DA041501NIDA NIH HHS R01 DA044207
6 · The paper itself

Abstract

backgroundBiological testing can be used to validate or detect underreported drug use. Since hair testing is increasingly used in survey research, we examined how the utility of hair testing compares to a more common method-urine testing.

methods532 adults (ages 18-29) reporting past-month heroin use and/or nonmedical prescription opioid use were surveyed about past-month use of various drugs. Participants were urine-tested and the majority (79.3%) provided a hair sample for analysis. We examined the utility of urine vs. hair-testing in detecting past-month use of various drugs.

resultsCompared to hair testing, urine testing was able to confirm higher proportions of self-reported use of heroin/opioids (85.5% vs. 80.9%), marijuana (73.9% vs. 22.9%), benzodiazepines (51.3% vs. 15.1%), and methadone (77.0% vs. 48.7%), while hair testing was more likely to detect reported cocaine use (66.3% vs. 48.0%) (Ps<.01). Compared to hair testing, urine testing was more likely to detect unreported use of marijuana (11.3% vs. 0.9%), and benzodiazepines (14.4% vs. 5.4%), and hair testing was more likely to detect unreported use of cocaine (27.0% vs. 5.8%) and oxycodone (19.7% vs. 1.4%) (Ps<.001). When added to urine testing, hair testing increased detection of reported and non-reported use of cocaine and oxycodone ranging from 14 to 22%.

conclusionsWhile hair testing is efficacious in detecting drug use in wide window periods (e.g., past-year use), it is less efficacious than urine testing when testing for past-month use of select drugs among opiate/opioid users. However, hair testing is particularly efficacious in detecting unreported use of cocaine and/or oxycodone.

Indexed as

Self ReportAdolescentAdultAnalgesics, OpioidCross-Sectional StudiesFemaleHairHumansMaleOpioid-Related DisordersSubstance Abuse DetectionSurveys and QuestionnairesYoung AdultAnalgesics, OpioidDrug testingEpidemiologyOpioidsResearch methods

Identifiers

PMID31146203
PMCPMC6588496
OpenAlexW2945431842

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.