Evidence map›Paper›PMID 31146182›Full record

ReviewCurrent opinion in immunology2019

Development, ontogeny, and maintenance of TCRαβ

Roland Ruscher, Kristin A Hogquist

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. A guide to thymic selection of T cells.Nature reviews. Immunology · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. A Beginner's Guide to T Cell Development.Methods in molecular biology (Clifton, N.J.) · 2023
    Review
  11. Article
  12. Article
  13. Bcl-2 Is Necessary to Counteract Bim and Promote Survival of TCRαβJournal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  14. Development and function of natural TCRFrontiers in immunology · 2022
    Review
  15. CD8ααSkin health and disease · 2021
    Article
  16. Review
  17. Preface: Unconventional T Cells in Health and Disease.Critical reviews in immunology · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Roland RuscherCenter for Immunology and Department of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, USA.
Kristin A HogquistCenter for Immunology and Department of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN, USA. Electronic address: hogqu001@umn.edu.

Funding

TCR signal strength in thymic selectionR37AI039560 · NIAID · UNIVERSITY OF MINNESOTA · PI HOGQUIST, KRISTIN A. · 2012 to 2021
$3.7M
Peptide induction of positive selectionR01AI039560 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI HOGQUIST, KRISTIN A. · 2001 to 2010
$3.1M
NIAID NIH HHS R01 AI039560NIAID NIH HHS R37 AI039560
6 · The paper itself

Abstract

The intestinal epithelium is the outermost cellular layer that separates the body from the gut lumen. The integrity of this protective mucosal barrier is crucial and maintained by specialized cells-intraepithelial lymphocytes (IEL). Much research has been conducted on these cells and our overall understanding of them is increasing rapidly. In this review we focus on the TCRαβ

Indexed as

AnimalsCD8 AntigensCD8-Positive T-LymphocytesHumansIntestinal MucosaIntraepithelial LymphocytesMorphogenesisReceptors, Antigen, T-Cell, alpha-betaThymus GlandT-Lymphocyte SubsetsCD8 AntigensReceptors, Antigen, T-Cell, alpha-beta

Identifiers

PMID31146182
PMCPMC6612447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.