Evidence map›Paper›PMID 31146033›Full record

ReviewActa biomaterialia2019

Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues.

Carolyn M Primus, Franklin R Tay, Li-Na Niu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Acta biomaterialia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. New Glass-Ceramics in the System CaMaterials (Basel, Switzerland) · 2025
    Article
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carolyn M PrimusDepartment of Endodontics, The Dental College of Georgia, Augusta University, USA. Electronic address: cprimus@me.com.
Franklin R TayDepartment of Endodontics, The Dental College of Georgia, Augusta University, USA.
Li-Na NiuDepartment of Endodontics, The Dental College of Georgia, Augusta University, USA; State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, China; The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, Hena, China.

Funding

Quick-Set Material-Phase IIR44DE020204 · NIDCR · PRIMUS CONSULTING · PI PRIMUS, CAROLYN MARGARET · 2012 to 2014
$1.3M
NIDCR NIH HHS R44 DE020204
6 · The paper itself

Abstract

Over 2500 articles and 200 reviews have been published on the bioactive tri/dicalcium silicate dental materials. The indications have expanded since their introduction in the 1990s from endodontic restorative and pulpal treatments to endodontic sealing and obturation. Bioactive ceramics, based on tri/dicalcium silicate cements, are now an indispensable part of the contemporary dental armamentarium for specialists including endodontists, pediatric dentists, oral surgeons andfor general dentists. This review emphasizes research on how these materials have conformed to international standards for dental materials ranging from biocompatibility (ISO 7405) to conformance as root canal sealers (ISO 6876). Potential future developments of alternative hydraulic materials were included. This review provides accurate materials science information on these important materials. STATEMENT OF SIGNIFICANCE: The broadening indications and the proliferation of tri/dicalcium silicate-based products make this relatively new dental material important for all dentists and biomaterials scientists. Presenting the variations in compositions, properties, indications and clinical performance enable clinicians to choose the material most suitable for their cases. Researchers may expand their bioactive investigations to further validate and improve materials and outcomes.

Indexed as

AnimalsBiocompatible MaterialsCalcium CompoundsDental PulpHumansMaterials TestingPeriapical TissueSilicatesBiocompatible MaterialsCalcium Compoundsdicalcium silicateSilicatestricalcium silicateBioactiveBioceramicBiosilicateDicalcium silicateHydraulic ceramic cement mineral trioxide aggregateTricalcium silicate

Identifiers

PMID31146033
PMCPMC6717675

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.