ArticleThe journal of allergy and clinical immunology. In practice
Serum Cadmium and Lead, Current Wheeze, and Lung Function in a Nationwide Study of Adults in the United States.
Article in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Mortality and hospitalization in contaminated sites with petrochemical and steel plants: a meta-regression ecological study.BMC public health · 2025Pooled it
- Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020Pooled it
- Optimization of Cadmium Adsorption onto a Cellulose Acetate-Clay Composite Membrane Using Box-Behnken Design.Molecules (Basel, Switzerland) · 2026Article
- Itching to know: the Microbiome, Allergic Disease, and Antimicrobial Chemicals.Current environmental health reports · 2026Review
- Harnessing Artificial Intelligence for Hypothesis Generation in Childhood Asthma: Insights from NHANES.Journal of respiratory biology and translational medicine · 2026Article
- Association between heavy metal exposure and chronic cough: the mediating roles of inflammation.Annals of medicine · 2025Article
- The predictive value of multiple urinary metals in evaluating death risk in asthmatic individuals: a prospective cohort study.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Heavy metals and their relationships with lung function and airway inflammation: insights from a population-based study.Journal of translational medicine · 2025Article
- Systemic inflammation mediates the relationship between urinary cadmium and chronic cough risk: findings based on multiple statistical models.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Joint association of indoor allergens, endotoxins, heavy metals, and parabens with allergy-related outcomes in U. S. adults.Frontiers in public health · 2025Article
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- Descriptive analysis to establish the prevalence of lead-associated chronic conditions among adult public health registry participants in Flint, Michigan: identifying disparities to support focused recovery efforts.BMJ public health · 2024Article
- Association between blood heavy metal element and all-cause mortality in asthmatic adults: a cohort study.Scientific reports · 2024Article
- Heavy Metal Exposure-Mediated Dysregulation of Sphingolipid Metabolism.Antioxidants (Basel, Switzerland) · 2024Article
- Environmental pollutant risk factors for worse COVID-19 related clinical outcomes in predominately hispanic and latino populations.Environmental research · 2024Article
- Assessing the Risk of Heart Attack: A Bayesian Kernel Machine Regression Analysis of Heavy Metal Mixtures.Research square · 2024Article
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- Article
- Prospective Study on the Association Between Blood Heavy Metal Levels and Pulmonary Function in University Students from a Medical College in Shandong Province, China.International journal of general medicine · 2024Article
- Associations between environmental heavy metals exposure and preserved ratio impaired spirometry in the U.S. adults.Environmental science and pollution research international · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundCadmium and lead are hazardous pollutants.
objectiveWe examined the relation between serum levels of cadmium and lead and current wheeze, current asthma, and lung function in US adults.
methodsA cross-sectional study of 13,888 adults aged 20 to 79 years in 2007-2012 National Health and Nutrition Examination Survey (NHANES) was considered. Multivariable logistic or linear regression was used for the analyses of current wheeze, current asthma, and lung function measures (forced expiratory volume in 1 second [FEV
resultsHigh levels of serum cadmium were significantly associated with current wheeze in all participants and in current smokers (odds ratio for fourth vs first quartile = 2.84, 95% confidence interval = 2.07-3.90, P
conclusionsOur findings suggest that exposure to cadmium is associated with an increased risk of wheeze and asthma in US adults who currently smoke. Moreover, our results suggest that exposure to cadmium or lead has negative effects on lung function in nonsmoking US adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.